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CHEBI:138649 - resolvin D4

ChEBI IDCHEBI:138649
ChEBI Nameresolvin D4
Stars
DefinitionA member of the class of resolvins that is (6E,8E,10Z,13Z,15E,19Z)-docosahexaenoic acid carrying three hydroxy substituents at positions 4, 5 and 17 (the 4S,5R,17S-stereoisomer).
Last Modified5 March 2018
SubmitterBijay
DownloadsMolfile
FormulaC22H32O5
Net Charge0
Average Mass376.493
Monoisotopic Mass376.22497
SMILESCC/C=C\C[C@H](O)/C=C/C=C\C/C=C\C=C\C=C\[C@@H](O)[C@@H](O)CCC(=O)O
InChIInChI=1S/C22H32O5/c1-2-3-11-14-19(23)15-12-9-7-5-4-6-8-10-13-16-20(24)21(25)17-18-22(26)27/h3-4,6-13,15-16,19-21,23-25H,2,5,14,17-18H2,1H3,(H,26,27)/b6-4-,9-7-,10-8+,11-3-,15-12+,16-13+/t19-,20+,21-/m0/s1
InChIKeyYKPLJNOOLKUEBS-RIYRYSNMSA-N
Species of MetaboliteComponentSourceComments
Homo sapiens (ncbitaxon:9606) - PubMed (26462421)
Roles Classification
Chemical Roles:
Bronsted acid  A molecular entity capable of donating a hydron to an acceptor (Brønsted base).
Bronsted acid  A molecular entity capable of donating a hydron to an acceptor (Brønsted base).
Biological Roles:
human xenobiotic metabolite  Any human metabolite produced by metabolism of a xenobiotic compound in humans.
specialised pro-resolving mediator  A class of cell signaling molecules enzymatically derived from n-3 long chain polyunsaturated fatty acids that have important roles in orchestrating the resolution of tissue inflammation.
Applications:
anti-inflammatory agent  Any compound that has anti-inflammatory effects.
specialised pro-resolving mediator  A class of cell signaling molecules enzymatically derived from n-3 long chain polyunsaturated fatty acids that have important roles in orchestrating the resolution of tissue inflammation.
ChEBI Ontology
Outgoing Relation(s)
resolvin D4 (CHEBI:138649) has role anti-inflammatory agent (CHEBI:67079)
resolvin D4 (CHEBI:138649) has role human xenobiotic metabolite (CHEBI:76967)
resolvin D4 (CHEBI:138649) is a hydroxy polyunsaturated fatty acid (CHEBI:140345)
resolvin D4 (CHEBI:138649) is a resolvin (CHEBI:132120)
resolvin D4 (CHEBI:138649) is a secondary allylic alcohol (CHEBI:134396)
resolvin D4 (CHEBI:138649) is a triol (CHEBI:27136)
IUPAC Name 
(4S,5R,6E,8E,10Z,13Z,15E,17S,19Z)-4,5,17-trihydroxydocosa-6,8,10,13,15,19-hexaenoic acid
Synonyms  Source
RvD4SUBMITTER
(4S,5R,6E,8E,10Z,13Z,15E,17S,19Z)-4,5,17-trihydroxydocosahexaenoic acidChEBI
Citations