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CHEBI:138179 - aspirin-triggered resolvin D1
| Formula | C22H32O5 |
| Net Charge | 0 |
| Average Mass | 376.493 |
| Monoisotopic Mass | 376.22497 |
| SMILES | CC/C=C\C[C@@H](O)/C=C/C=C\C=C\C=C\[C@@H](O)[C@@H](O)C/C=C\CCC(=O)O |
| InChI | InChI=1S/C22H32O5/c1-2-3-9-14-19(23)15-10-6-4-5-7-11-16-20(24)21(25)17-12-8-13-18-22(26)27/h3-12,15-16,19-21,23-25H,2,13-14,17-18H2,1H3,(H,26,27)/b6-4-,7-5+,9-3-,12-8-,15-10+,16-11+/t19-,20-,21+/m1/s1 |
| InChIKey | OIWTWACQMDFHJG-BJEBZIPWSA-N |
| Species of Metabolite | Component | Source | Comments |
|---|---|---|---|
| Homo sapiens (ncbitaxon:9606) | - | PubMed (17244615) |
| Roles Classification |
|---|
| Chemical Roles: | Bronsted acid A molecular entity capable of donating a hydron to an acceptor (Brønsted base). Bronsted acid A molecular entity capable of donating a hydron to an acceptor (Brønsted base). |
| Biological Roles: | human xenobiotic metabolite Any human metabolite produced by metabolism of a xenobiotic compound in humans. TGFbeta receptor antagonist An antagonist that binds to and deactivates TGFβ receptors. antiviral agent A substance that destroys or inhibits replication of viruses. analgesic An agent capable of relieving pain without the loss of consciousness or without producing anaesthesia. In addition, analgesic is a role played by a compound which is exhibited by a capability to cause a reduction of pain symptoms. specialised pro-resolving mediator A class of cell signaling molecules enzymatically derived from n-3 long chain polyunsaturated fatty acids that have important roles in orchestrating the resolution of tissue inflammation. |
| Applications: | anti-inflammatory agent Any compound that has anti-inflammatory effects. nephroprotective agent Any protective agent that is able to prevent damage to the kidney. analgesic An agent capable of relieving pain without the loss of consciousness or without producing anaesthesia. In addition, analgesic is a role played by a compound which is exhibited by a capability to cause a reduction of pain symptoms. anti-allergic agent A drug used to treat allergic reactions. specialised pro-resolving mediator A class of cell signaling molecules enzymatically derived from n-3 long chain polyunsaturated fatty acids that have important roles in orchestrating the resolution of tissue inflammation. |
| ChEBI Ontology |
|---|
| Outgoing Relation(s) |
| aspirin-triggered resolvin D1 (CHEBI:138179) has role analgesic (CHEBI:35480) |
| aspirin-triggered resolvin D1 (CHEBI:138179) has role anti-allergic agent (CHEBI:50857) |
| aspirin-triggered resolvin D1 (CHEBI:138179) has role anti-inflammatory agent (CHEBI:67079) |
| aspirin-triggered resolvin D1 (CHEBI:138179) has role antiviral agent (CHEBI:22587) |
| aspirin-triggered resolvin D1 (CHEBI:138179) has role human xenobiotic metabolite (CHEBI:76967) |
| aspirin-triggered resolvin D1 (CHEBI:138179) has role nephroprotective agent (CHEBI:76595) |
| aspirin-triggered resolvin D1 (CHEBI:138179) has role TGFβ receptor antagonist (CHEBI:91202) |
| aspirin-triggered resolvin D1 (CHEBI:138179) is a hydroxy polyunsaturated fatty acid (CHEBI:140345) |
| aspirin-triggered resolvin D1 (CHEBI:138179) is a resolvin (CHEBI:132120) |
| aspirin-triggered resolvin D1 (CHEBI:138179) is a secondary allylic alcohol (CHEBI:134396) |
| IUPAC Name |
|---|
| (4Z,7S,8R,9E,11E,13Z,15E,17R,19Z)-7,8,17-trihydroxydocosa-4,9,11,13,15,19-hexaenoic acid |
| Synonyms | Source |
|---|---|
| 17-epi-resolvin D1 | ChEBI |
| 17(R)-resolvin D1 | ChEBI |
| 17(R)-RvD1 | ChEBI |
| (4Z,7S,8R,9E,11E,13Z,15E,17R,19Z)-7,8,17-trihydroxydocosahexaenoic acid | ChEBI |
| 7S,8R,17R-trihydroxy-4Z,9E,11E,13Z,15E,19Z-docosahexaenoic acid | LIPID MAPS |
| AT-Resolvin D1 | LIPID MAPS |
| Manual Xrefs | Databases |
|---|---|
| LMFA04030005 | LIPID MAPS |
| Registry Numbers | Sources |
|---|---|
| Reaxys:24477830 | Reaxys |
| Citations |
|---|