EMBL-EBI | Chemical Biology | ChEBI

Example searches: iron*, InChI=1S/CH4O/c1-2/h2H,1H3, caffeine | Advanced Search

CHEBI:137034 - (18S)-resolvin E2

ChEBI IDCHEBI:137034
ChEBI Name(18S)-resolvin E2
Stars
ASCII Name(18S)-resolvin E2
DefinitionA member of the class of resolvins that is (6E,8Z,11Z,14Z,16E)-icosapentaenoic acid carrying two hydroxy substituents at positions 5 and 18 (the 5S,18S stereoisomer).
Last Modified5 March 2018
SubmitterSteve
DownloadsMolfile
FormulaC20H30O4
Net Charge0
Average Mass334.456
Monoisotopic Mass334.21441
SMILESCC[C@H](O)/C=C/C=C\C/C=C\C/C=C\C=C\[C@@H](O)CCCC(=O)O
InChIInChI=1S/C20H30O4/c1-2-18(21)14-11-9-7-5-3-4-6-8-10-12-15-19(22)16-13-17-20(23)24/h3-4,7-12,14-15,18-19,21-22H,2,5-6,13,16-17H2,1H3,(H,23,24)/b4-3-,9-7-,10-8-,14-11+,15-12+/t18-,19+/m0/s1
InChIKeyKPRHYAOSTOHNQA-SFHVADPASA-N
Species of MetaboliteComponentSourceComments
Homo Sapiens (ncbitaxon:9606) - PubMed (21206090)
Roles Classification
Chemical Roles:
Bronsted acid  A molecular entity capable of donating a hydron to an acceptor (Brønsted base).
Bronsted acid  A molecular entity capable of donating a hydron to an acceptor (Brønsted base).
Biological Roles:
human xenobiotic metabolite  Any human metabolite produced by metabolism of a xenobiotic compound in humans.
specialised pro-resolving mediator  A class of cell signaling molecules enzymatically derived from n-3 long chain polyunsaturated fatty acids that have important roles in orchestrating the resolution of tissue inflammation.
Applications:
anti-inflammatory agent  Any compound that has anti-inflammatory effects.
specialised pro-resolving mediator  A class of cell signaling molecules enzymatically derived from n-3 long chain polyunsaturated fatty acids that have important roles in orchestrating the resolution of tissue inflammation.
ChEBI Ontology
Outgoing Relation(s)
(18S)-resolvin E2 (CHEBI:137034) has role anti-inflammatory agent (CHEBI:67079)
(18S)-resolvin E2 (CHEBI:137034) has role human xenobiotic metabolite (CHEBI:76967)
(18S)-resolvin E2 (CHEBI:137034) is a diol (CHEBI:23824)
(18S)-resolvin E2 (CHEBI:137034) is a hydroxy polyunsaturated fatty acid (CHEBI:140345)
(18S)-resolvin E2 (CHEBI:137034) is a resolvin (CHEBI:132120)
(18S)-resolvin E2 (CHEBI:137034) is a secondary allylic alcohol (CHEBI:134396)
(18S)-resolvin E2 (CHEBI:137034) is conjugate acid of (18S)-resolvin E2(1−) (CHEBI:136056)
Incoming Relation(s)
(18S)-resolvin E2(1−) (CHEBI:136056) is conjugate base of (18S)-resolvin E2 (CHEBI:137034)
IUPAC Name 
(5S,6E,8Z,11Z,14Z,16E,18S)-5,18-dihydroxyicosa-6,8,11,14,16-pentaenoic acid
Synonyms  Source
(5S,6E,8Z,11Z,14Z,16E,18S)-5,18-dihydroxyicosapentaenoic acidChEBI
18S-resolvin E2ChEBI
(5S,18S)-dihydroxy-(6E,8Z,11Z,14Z,16E)-eicosapentaenoic acidChEBI
18S-RvE2ChEBI
(5S,18S)-dihydroxy-(6E,8Z,11Z,14Z,16E)-icosapentaenoic acidChEBI
5S,18S-dihydroxy-6E,8Z,11Z,14Z,16E-eicosapentaenoic acidLIPID MAPS
Manual XrefsDatabases
LMFA03070036LIPID MAPS
Citations