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CHEBI:136532 - 8-azahypoxanthine

ChEBI IDCHEBI:136532
ChEBI Name8-azahypoxanthine
Stars
DefinitionA triazolopyrimidine that consists of 1,4-dihydro-7H-[1,2,3]triazolo[4,5-d]pyrimidine bearing an oxo substituent at position 7.
Last Modified13 March 2017
SubmitterGareth Owen
DownloadsMolfile
FormulaC4H3N5O
Net Charge0
Average Mass137.102
Monoisotopic Mass137.03376
SMILESO=c1ncnc2nnnc12
InChIInChI=1S/C4H3N5O/c10-4-2-3(5-1-6-4)8-9-7-2/h1H,(H2,5,6,7,8,9,10)
InChIKeyOEEYCNOOAHGFHL-UHFFFAOYSA-N
Roles Classification
Biological Roles:
antimalarial  A drug used in the treatment of malaria. Antimalarials are usually classified on the basis of their action against Plasmodia at different stages in their life cycle in the human.
EC 2.4.2.8 (hypoxanthine phosphoribosyltransferase) inhibitor  An EC 2.4.2.* (pentosyltransferase) inhibitor that interferes with the action of hypoxanthine phosphoribosyltransferase (EC 2.4.2.8).
Application:
antimalarial  A drug used in the treatment of malaria. Antimalarials are usually classified on the basis of their action against Plasmodia at different stages in their life cycle in the human.
ChEBI Ontology
Outgoing Relation(s)
8-azahypoxanthine (CHEBI:136532) has role antimalarial (CHEBI:38068)
8-azahypoxanthine (CHEBI:136532) has role EC 2.4.2.8 (hypoxanthine phosphoribosyltransferase) inhibitor (CHEBI:136537)
8-azahypoxanthine (CHEBI:136532) is a nucleobase analogue (CHEBI:67142)
8-azahypoxanthine (CHEBI:136532) is a triazolopyrimidines (CHEBI:48435)
IUPAC Name 
1,4-dihydro-7H-[1,2,3]triazolo[4,5-d]pyrimidin-7-one
Synonyms  Source
1H-1,2,3-triazolo(4,5-d)pyrimidin-7-olChemIDplus
7-hydroxy-1,2,3,4,6-pentaazaindeneChemIDplus
azahypoxanthineChemIDplus
8-azaHxChEBI
Registry NumbersSources
Reaxys:513873Reaxys
CAS:2683-90-1ChemIDplus
Citations