ambrisentan (CHEBI:135949)

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CHEBI:135949 - ambrisentan

Formula	C22H22N2O4
Net Charge	0
Average Mass	378.428
Monoisotopic Mass	378.15796
SMILES	COC(c1ccccc1)(c1ccccc1)[C@H](Oc1nc(C)cc(C)n1)C(=O)O
InChI	InChI=1S/C22H22N2O4/c1-15-14-16(2)24-21(23-15)28-19(20(25)26)22(27-3,17-10-6-4-7-11-17)18-12-8-5-9-13-18/h4-14,19H,1-3H3,(H,25,26)/t19-/m1/s1
InChIKey	OUJTZYPIHDYQMC-LJQANCHMSA-N

Roles Classification

antiviral agent A substance that destroys or inhibits replication of viruses.

antifibrotic agent Any agent which acts to reduce fibrosis.

anti-asthmatic agent Any compound that has anti-asthmatic effects.

antihypertensive agent Any drug used in the treatment of acute or chronic vascular hypertension regardless of pharmacological mechanism.

anti-anaemic agent A compound which increases either the number of red cells or the amount of haemoglobin in the blood.

cardiovascular drug A drug that affects the rate or intensity of cardiac contraction, blood vessel diameter or blood volume.

ChEBI Ontology

Outgoing Relation(s)
	ambrisentan (CHEBI:135949) has role anti-anaemic agent (CHEBI:75835)
	ambrisentan (CHEBI:135949) has role anti-asthmatic agent (CHEBI:65023)
	ambrisentan (CHEBI:135949) has role antifibrotic agent (CHEBI:233423)
	ambrisentan (CHEBI:135949) has role antihypertensive agent (CHEBI:35674)
	ambrisentan (CHEBI:135949) has role antiviral agent (CHEBI:22587)
	ambrisentan (CHEBI:135949) has role cardiovascular drug (CHEBI:35554)
	ambrisentan (CHEBI:135949) is a diarylmethane (CHEBI:51614)

Brand Name	Source
Ambrisentan mylan	ChEMBL

Manual Xrefs	Databases
4337	DrugCentral

Registry Numbers	Sources
CAS:177036-94-1	DrugCentral

Citations