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CHEBI:135864 - methylprednisolone suleptanate

ChEBI IDCHEBI:135864
ChEBI Namemethylprednisolone suleptanate
Stars
DefinitionAn organic sodium salt that is the monosodium salt of methylprednisolone 21-suleptanic acid ester. It is a prodrug of methylprednisolone developed by Pharmacia Corp for the treatment of asthma.
Last Modified9 September 2020
DownloadsMolfile
FormulaC33H48NO10S.Na
Net Charge0
Average Mass673.801
Monoisotopic Mass673.28966
SMILES[H][C@@]12CC[C@](O)(C(=O)COC(=O)CCCCCCC(=O)N(C)CCS(=O)(=O)[O-])[C@@]1(C)C[C@H](O)[C@@]1([H])[C@@]2([H])C[C@H](C)C2=CC(=O)C=C[C@@]21C.[Na+]
InChIInChI=1S/C33H49NO10S.Na/c1-21-17-23-24-12-14-33(40,32(24,3)19-26(36)30(23)31(2)13-11-22(35)18-25(21)31)27(37)20-44-29(39)10-8-6-5-7-9-28(38)34(4)15-16-45(41,42)43;/h11,13,18,21,23-24,26,30,36,40H,5-10,12,14-17,19-20H2,1-4H3,(H,41,42,43);/q;+1/p-1/t21-,23-,24-,26-,30+,31-,32-,33-;/m0./s1
InChIKeyCDMLLMOLWUKNEK-AOHDELFNSA-M
Wikipedia
Roles Classification
Biological Role:
glucocorticoid receptor agonist  An agonist that selectively binds to and activates a glucocorticoid receptor.
Applications:
prodrug  A compound that, on administration, must undergo chemical conversion by metabolic processes before becoming the pharmacologically active drug for which it is a prodrug.
anti-inflammatory agent  Any compound that has anti-inflammatory effects.
anti-asthmatic drug  A drug used to treat asthma.
ChEBI Ontology
Outgoing Relation(s)
methylprednisolone suleptanate (CHEBI:135864) has part methylprednisolone 21-suleptanic acid ester(1−) (CHEBI:156481)
methylprednisolone suleptanate (CHEBI:135864) has role anti-asthmatic drug (CHEBI:49167)
methylprednisolone suleptanate (CHEBI:135864) has role anti-inflammatory agent (CHEBI:67079)
methylprednisolone suleptanate (CHEBI:135864) has role glucocorticoid receptor agonist (CHEBI:63562)
methylprednisolone suleptanate (CHEBI:135864) has role prodrug (CHEBI:50266)
methylprednisolone suleptanate (CHEBI:135864) is a organic sodium salt (CHEBI:38700)
IUPAC Name 
sodium 2-[{8-[(11β,17-dihydroxy-6α-methyl-3,20-dioxopregna-1,4-dien-21-yl)oxy]-8-oxooctanoyl}(methyl)amino]ethanesulfonate
INNs  Source
suleptanato de metilprednisolonaWHO MedNet
suleptanate de méthylprednisoloneWHO MedNet
methylprednisoloni suleptanasWHO MedNet
methylprednisolone suleptanateWHO MedNet
Synonyms  Source
methylprednisolone suleptanate sodium saltDrugCentral
methylprednisolone suleptanate sodiumDrugCentral
U-67590AChEBI
U-67,590AChemIDplus
PNU-67590AChEBI
PNU 67590AChemIDplus
Brand Names  Source
PromedrolChemIDplus
MedrosolChemIDplus
Manual XrefsDatabases
1772DrugCentral
Methylprednisolone_suleptanateWikipedia
D05002KEGG DRUG
Registry NumbersSources
CAS:90350-40-6ChemIDplus
Citations