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CHEBI:135859 - efonidipine

ChEBI IDCHEBI:135859
ChEBI Nameefonidipine
Stars
DefinitionA racemate comprising of equimolar amounts of (R)- and (S)-efonidipine. It is a antihypertensive drug and a dual T-type and L-type calcium channel blocker.
Last Modified25 February 2020
FormulaC34H38N3O7P
Net Charge0
Average Mass631.666
Monoisotopic Mass631.24474
Wikipedia
Roles Classification
Biological Role:
calcium channel blocker  One of a class of drugs that acts by selective inhibition of calcium influx through cell membranes or on the release and binding of calcium in intracellular pools.
Applications:
antihypertensive agent  Any drug used in the treatment of acute or chronic vascular hypertension regardless of pharmacological mechanism.
vasodilator agent  A drug used to cause dilation of the blood vessels.
ChEBI Ontology
Outgoing Relation(s)
efonidipine (CHEBI:135859) has part (R)-efonidipine (CHEBI:146219)
efonidipine (CHEBI:135859) has part (S)-efonidipine (CHEBI:146220)
efonidipine (CHEBI:135859) has role antihypertensive agent (CHEBI:35674)
efonidipine (CHEBI:135859) has role calcium channel blocker (CHEBI:38215)
efonidipine (CHEBI:135859) has role vasodilator agent (CHEBI:35620)
efonidipine (CHEBI:135859) is a racemate (CHEBI:60911)
IUPAC Name 
rac-2-[benzyl(phenyl)amino]ethyl 5-(5,5-dimethyl-2-oxido-1,3,2-dioxaphosphinan-2-yl)-2,6-dimethyl-4-(3-nitrophenyl)-1,4-dihydropyridine-3-carboxylate
INNs  Source
efonidipinumWHO MedNet
efonidipineWHO MedNet
éfonidipineWHO MedNet
efonidipinoWHO MedNet
Synonyms  Source
(±)-efonidipineChEBI
racemic efonidipineChEBI
rac-efonidipineChEBI
NZ-105DrugBank
NZ105ChEBI
Manual XrefsDatabases
992DrugCentral
DB09235DrugBank
D07886KEGG DRUG
EfonidipineWikipedia
Registry NumbersSources
CAS:111011-63-3ChemIDplus
Citations