EMBL-EBI | Chemical Biology | ChEBI

Example searches: iron*, InChI=1S/CH4O/c1-2/h2H,1H3, caffeine | Advanced Search

CHEBI:135859 - efonidipine

ChEBI IDCHEBI:135859
ChEBI Nameefonidipine
Stars
DefinitionA racemate comprising of equimolar amounts of (R)- and (S)-efonidipine. It is a antihypertensive drug and a dual T-type and L-type calcium channel blocker.
Last Modified25 February 2020
FormulaC34H38N3O7P
Net Charge0
Average Mass631.666
Monoisotopic Mass631.24474
Wikipedia
Roles Classification
Biological Role:
calcium channel blocker  One of a class of drugs that acts by selective inhibition of calcium influx through cell membranes or on the release and binding of calcium in intracellular pools.
Applications:
vasodilator agent  A drug used to cause dilation of the blood vessels.
antihypertensive agent  Any drug used in the treatment of acute or chronic vascular hypertension regardless of pharmacological mechanism.
ChEBI Ontology
Outgoing Relation(s)
efonidipine (CHEBI:135859) has part (R)-efonidipine (CHEBI:146219)
efonidipine (CHEBI:135859) has part (S)-efonidipine (CHEBI:146220)
efonidipine (CHEBI:135859) has role antihypertensive agent (CHEBI:35674)
efonidipine (CHEBI:135859) has role calcium channel blocker (CHEBI:38215)
efonidipine (CHEBI:135859) has role vasodilator agent (CHEBI:35620)
efonidipine (CHEBI:135859) is a racemate (CHEBI:60911)
IUPAC Name 
rac-2-[benzyl(phenyl)amino]ethyl 5-(5,5-dimethyl-2-oxido-1,3,2-dioxaphosphinan-2-yl)-2,6-dimethyl-4-(3-nitrophenyl)-1,4-dihydropyridine-3-carboxylate
INNs  Source
efonidipineWHO MedNet
éfonidipineWHO MedNet
efonidipinoWHO MedNet
efonidipinumWHO MedNet
Synonyms  Source
(±)-efonidipineChEBI
rac-efonidipineChEBI
NZ-105DrugBank
NZ105ChEBI
racemic efonidipineChEBI
Manual XrefsDatabases
992DrugCentral
D07886KEGG DRUG
DB09235DrugBank
EfonidipineWikipedia
Registry NumbersSources
CAS:111011-63-3ChemIDplus
Citations