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CHEBI:135621 - metaclazepam

ChEBI IDCHEBI:135621
ChEBI Namemetaclazepam
Stars
Last Modified23 February 2017
DownloadsMolfile
FormulaC18H18BrClN2O
Net Charge0
Average Mass393.712
Monoisotopic Mass392.02910
SMILESCOCC1CN=C(c2ccccc2Cl)c2cc(Br)ccc2N1C
InChIInChI=1S/C18H18BrClN2O/c1-22-13(11-23-2)10-21-18(14-5-3-4-6-16(14)20)15-9-12(19)7-8-17(15)22/h3-9,13H,10-11H2,1-2H3
InChIKeyWABYCCJHARSRBH-UHFFFAOYSA-N
Roles Classification
Biological Role:
GABA modulator  A substance that does not act as agonist or antagonist but does affect the gamma-aminobutyric acid receptor-ionophore complex. GABA-A receptors appear to have at least three allosteric sites at which modulators act: a site at which benzodiazepines act by increasing the opening frequency of gamma-aminobutyric acid-activated chloride channels; a site at which barbiturates act to prolong the duration of channel opening; and a site at which some steroids may act.
Application:
GABA modulator  A substance that does not act as agonist or antagonist but does affect the gamma-aminobutyric acid receptor-ionophore complex. GABA-A receptors appear to have at least three allosteric sites at which modulators act: a site at which benzodiazepines act by increasing the opening frequency of gamma-aminobutyric acid-activated chloride channels; a site at which barbiturates act to prolong the duration of channel opening; and a site at which some steroids may act.
ChEBI Ontology
Outgoing Relation(s)
metaclazepam (CHEBI:135621) is a benzodiazepine (CHEBI:22720)
Synonyms  Source
brometazepamDrugCentral
Ka 2527DrugCentral
metaclazepam hydrochlorideDrugCentral
metuclazepamDrugCentral
metaclazepam HClDrugCentral
Ka-2527DrugCentral
Manual XrefsDatabases
1716DrugCentral
Registry NumbersSources
CAS:84031-17-4DrugCentral