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CHEBI:135595 - fendosal

ChEBI IDCHEBI:135595
ChEBI Namefendosal
Stars
DefinitionA benzoindole that is 4,5-dihydro-3H-benzo[e]indole in which the nitrogen is substituted by a 3-carboxy-4-hydroxyphenyl group. A non-narcotic analgesic and non-steroidal anti-inflammatory drug, it has greater analgesic and inflammatory responses than aspirin but with less gastrointestinal toxicity.
Last Modified22 January 2018
DownloadsMolfile
FormulaC25H19NO3
Net Charge0
Average Mass381.431
Monoisotopic Mass381.13649
SMILESO=C(O)c1cc(-n2c(-c3ccccc3)cc3c2CCc2ccccc2-3)ccc1O
InChIInChI=1S/C25H19NO3/c27-24-13-11-18(14-21(24)25(28)29)26-22-12-10-16-6-4-5-9-19(16)20(22)15-23(26)17-7-2-1-3-8-17/h1-9,11,13-15,27H,10,12H2,(H,28,29)
InChIKeyHAWWPSYXSLJRBO-UHFFFAOYSA-N
Roles Classification
Chemical Role:
Bronsted acid  A molecular entity capable of donating a hydron to an acceptor (Brønsted base).
Biological Role:
non-narcotic analgesic  A drug that has principally analgesic, antipyretic and anti-inflammatory actions. Non-narcotic analgesics do not bind to opioid receptors.
Applications:
non-steroidal anti-inflammatory drug  An anti-inflammatory drug that is not a steroid. In addition to anti-inflammatory actions, non-steroidal anti-inflammatory drugs have analgesic, antipyretic, and platelet-inhibitory actions. They act by blocking the synthesis of prostaglandins by inhibiting cyclooxygenase, which converts arachidonic acid to cyclic endoperoxides, precursors of prostaglandins.
non-narcotic analgesic  A drug that has principally analgesic, antipyretic and anti-inflammatory actions. Non-narcotic analgesics do not bind to opioid receptors.
ChEBI Ontology
Outgoing Relation(s)
fendosal (CHEBI:135595) has role non-narcotic analgesic (CHEBI:35481)
fendosal (CHEBI:135595) has role non-steroidal anti-inflammatory drug (CHEBI:35475)
fendosal (CHEBI:135595) is a benzoindole (CHEBI:38111)
fendosal (CHEBI:135595) is a monohydroxybenzoic acid (CHEBI:25389)
fendosal (CHEBI:135595) is a pyrroles (CHEBI:26455)
IUPAC Name 
2-hydroxy-5-(2-phenyl-4,5-dihydro-3H-benzo[e]indol-3-yl)benzoic acid
INNs  Source
fendosalWHO MedNet
fendosalWHO MedNet
fendosalumWHO MedNet
fendosalWHO MedNet
Synonyms  Source
HP 129DrugCentral
3-(3-carboxy-4-hydroxyphenyl)-2-phenyl-4,5-dihydro-3H-benz(e)indoleChemIDplus
5-(4,5-dihydro-2-phenyl-3H-benz(e)indol-3-yl)-2-hydroxybenzoic acidChemIDplus
5-(4,5-dihydro-2-phenyl-3H-benzo[e]indol-3-yl)salicylic acidChEBI
Brand Name  Source
AlnovinKEGG DRUG
Manual XrefsDatabases
3224DrugCentral
D04145KEGG DRUG
Registry NumbersSources
Reaxys:1665211Reaxys
CAS:53597-27-6DrugCentral
CAS:53597-27-6ChemIDplus
Citations