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CHEBI:135556 - ketazolam

ChEBI IDCHEBI:135556
ChEBI Nameketazolam
Stars
Last Modified23 February 2017
DownloadsMolfile
FormulaC20H17ClN2O3
Net Charge0
Average Mass368.820
Monoisotopic Mass368.09277
SMILESCC1=CC(=O)N2CC(=O)N(C)c3ccc(Cl)cc3C2(c2ccccc2)O1
InChIInChI=1S/C20H17ClN2O3/c1-13-10-18(24)23-12-19(25)22(2)17-9-8-15(21)11-16(17)20(23,26-13)14-6-4-3-5-7-14/h3-11H,12H2,1-2H3
InChIKeyPWAJCNITSBZRBL-UHFFFAOYSA-N
Roles Classification
Biological Role:
GABA modulator  A substance that does not act as agonist or antagonist but does affect the gamma-aminobutyric acid receptor-ionophore complex. GABA-A receptors appear to have at least three allosteric sites at which modulators act: a site at which benzodiazepines act by increasing the opening frequency of gamma-aminobutyric acid-activated chloride channels; a site at which barbiturates act to prolong the duration of channel opening; and a site at which some steroids may act.
Application:
GABA modulator  A substance that does not act as agonist or antagonist but does affect the gamma-aminobutyric acid receptor-ionophore complex. GABA-A receptors appear to have at least three allosteric sites at which modulators act: a site at which benzodiazepines act by increasing the opening frequency of gamma-aminobutyric acid-activated chloride channels; a site at which barbiturates act to prolong the duration of channel opening; and a site at which some steroids may act.
ChEBI Ontology
Outgoing Relation(s)
ketazolam (CHEBI:135556) is a benzodiazepine (CHEBI:22720)
Synonym  Source
loftranDrugCentral
Manual XrefsDatabases
1525DrugCentral
HMDB0015526HMDB
Registry NumbersSources
CAS:27223-35-4DrugCentral