EMBL-EBI | Chemical Biology | ChEBI
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| Formula | C18H13ClN2O |
| Net Charge | 0 |
| Average Mass | 308.768 |
| Monoisotopic Mass | 308.07164 |
| SMILES | C#CCN1C(=O)CN=C(c2ccccc2)c2cc(Cl)ccc21 |
| InChI | InChI=1S/C18H13ClN2O/c1-2-10-21-16-9-8-14(19)11-15(16)18(20-12-17(21)22)13-6-4-3-5-7-13/h1,3-9,11H,10,12H2 |
| InChIKey | MFZOSKPPVCIFMT-UHFFFAOYSA-N |
| Roles Classification |
|---|
| Biological Role: | GABA modulator A substance that does not act as agonist or antagonist but does affect the gamma-aminobutyric acid receptor-ionophore complex. GABA-A receptors appear to have at least three allosteric sites at which modulators act: a site at which benzodiazepines act by increasing the opening frequency of gamma-aminobutyric acid-activated chloride channels; a site at which barbiturates act to prolong the duration of channel opening; and a site at which some steroids may act. |
| Application: | GABA modulator A substance that does not act as agonist or antagonist but does affect the gamma-aminobutyric acid receptor-ionophore complex. GABA-A receptors appear to have at least three allosteric sites at which modulators act: a site at which benzodiazepines act by increasing the opening frequency of gamma-aminobutyric acid-activated chloride channels; a site at which barbiturates act to prolong the duration of channel opening; and a site at which some steroids may act. |
| ChEBI Ontology |
|---|
| Outgoing Relation(s) |
| pinazepam (CHEBI:135315) is a benzodiazepine (CHEBI:22720) |
| Synonym | Source |
|---|---|
| domar | DrugCentral |
| Manual Xrefs | Databases |
|---|---|
| 2175 | DrugCentral |
| HMDB0041988 | HMDB |
| Registry Numbers | Sources |
|---|---|
| CAS:52463-83-9 | DrugCentral |