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CHEBI:135207 - clofedanol

ChEBI IDCHEBI:135207
ChEBI Nameclofedanol
Stars
DefinitionA diarylmethane that is 2-chlorophenyl(phenyl)methane substituted on the methane carbon by a 2-(dimethylamino)ethyl group. Used in the treatment of dry cough, it suppresses the cough reflex by a direct effect on the cough centre in the medulla of the brain.
Last Modified14 June 2018
DownloadsMolfile
FormulaC17H20ClNO
Net Charge0
Average Mass289.806
Monoisotopic Mass289.12334
SMILESCN(C)CCC(O)(c1ccccc1)c1ccccc1Cl
InChIInChI=1S/C17H20ClNO/c1-19(2)13-12-17(20,14-8-4-3-5-9-14)15-10-6-7-11-16(15)18/h3-11,20H,12-13H2,1-2H3
InChIKeyWRCHFMBCVFFYEQ-UHFFFAOYSA-N
Wikipedia
Roles Classification
Chemical Role:
Bronsted base  A molecular entity capable of accepting a hydron from a donor (Brønsted acid).
Application:
antitussive  An agent that suppresses cough. Antitussives have a central or a peripheral action on the cough reflex, or a combination of both. Compare with expectorants, which are considered to increase the volume of secretions in the respiratory tract, so facilitating their removal by ciliary action and coughing, and mucolytics, which decrease the viscosity of mucus, facilitating its removal by ciliary action and expectoration.
ChEBI Ontology
Outgoing Relation(s)
clofedanol (CHEBI:135207) has role antitussive (CHEBI:51177)
clofedanol (CHEBI:135207) is a diarylmethane (CHEBI:51614)
clofedanol (CHEBI:135207) is a tertiary amino compound (CHEBI:50996)
clofedanol (CHEBI:135207) is conjugate base of clofedanol(1+) (CHEBI:187895)
Incoming Relation(s)
clofedanol(1+) (CHEBI:187895) is conjugate acid of clofedanol (CHEBI:135207)
IUPAC Name 
1-(2-chlorophenyl)-3-(dimethylamino)-1-phenylpropan-1-ol
INNs  Source
clofedanolChemIDplus
clofedanolumChEBI
clofedanolWHO MedNet
clofédanolWHO MedNet
Synonym  Source
chlophedianolDrugCentral
Manual XrefsDatabases
585DrugCentral
DB04837DrugBank
CN101844989Patent
ClofedanolWikipedia
D07721KEGG DRUG
Registry NumbersSources
Reaxys:2813922Reaxys
CAS:791-35-5DrugCentral
CAS:791-35-5ChemIDplus
Citations