CHEBI:135197 - desalkylflurazepam

ChEBI IDCHEBI:135197
ChEBI Namedesalkylflurazepam
Stars
Last Modified23 February 2017
DownloadsMolfile
FormulaC15H10ClFN2O
Net Charge0
Average Mass288.709
Monoisotopic Mass288.04657
SMILESO=C1CN=C(c2ccccc2F)c2cc(Cl)ccc2N1
InChIInChI=1S/C15H10ClFN2O/c16-9-5-6-13-11(7-9)15(18-8-14(20)19-13)10-3-1-2-4-12(10)17/h1-7H,8H2,(H,19,20)
InChIKeyUVCOILFBWYKHHB-UHFFFAOYSA-N
Roles Classification
Biological Role:
GABA modulator  A substance that does not act as agonist or antagonist but does affect the gamma-aminobutyric acid receptor-ionophore complex. GABA-A receptors appear to have at least three allosteric sites at which modulators act: a site at which benzodiazepines act by increasing the opening frequency of gamma-aminobutyric acid-activated chloride channels; a site at which barbiturates act to prolong the duration of channel opening; and a site at which some steroids may act.
Application:
GABA modulator  A substance that does not act as agonist or antagonist but does affect the gamma-aminobutyric acid receptor-ionophore complex. GABA-A receptors appear to have at least three allosteric sites at which modulators act: a site at which benzodiazepines act by increasing the opening frequency of gamma-aminobutyric acid-activated chloride channels; a site at which barbiturates act to prolong the duration of channel opening; and a site at which some steroids may act.
ChEBI Ontology
Outgoing Relation(s)
desalkylflurazepam (CHEBI:135197) is a benzodiazepine (CHEBI:22720)
Synonyms  Source
norflutoprazepamDrugCentral
descarbethoxyloflazepateDrugCentral
norfludiazepamDrugCentral
dealkylflurazepamDrugCentral
norflurazepamDrugCentral
Manual XrefsDatabases
809DrugCentral
HMDB0061161HMDB
Registry NumbersSources
CAS:2886-65-9DrugCentral