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CHEBI:134870 - toloxatone

ChEBI IDCHEBI:134870
ChEBI Nametoloxatone
Stars
DefinitionA racemate consisting of equimolar amounts of (R)- and (S)-toloxatone. It is a reversible monoamine oxidase A inhibitor and antidepressant.
Last Modified2 October 2020
FormulaC11H13NO3
Net Charge0
Average Mass207.229
Monoisotopic Mass207.08954
Wikipedia
Roles Classification
Biological Role:
EC 1.4.3.4 (monoamine oxidase) inhibitor  An EC 1.4.3.* (oxidoreductase acting on donor CH-NH2 group, oxygen as acceptor) inhibitor that interferes with the action of monoamine oxidase (EC 1.4.3.4).
Application:
antidepressant  Antidepressants are mood-stimulating drugs used primarily in the treatment of affective disorders and related conditions.
ChEBI Ontology
Outgoing Relation(s)
toloxatone (CHEBI:134870) has part (R)-toloxatone (CHEBI:156573)
toloxatone (CHEBI:134870) has part (S)-toloxatone (CHEBI:156574)
toloxatone (CHEBI:134870) has role antidepressant (CHEBI:35469)
toloxatone (CHEBI:134870) has role EC 1.4.3.4 (monoamine oxidase) inhibitor (CHEBI:38623)
toloxatone (CHEBI:134870) is a racemate (CHEBI:60911)
IUPAC Name 
rac-5-(hydroxymethyl)-3-(3-methylphenyl)-1,3-oxazolidin-2-one
INNs  Source
toloxatoneWHO MedNet
toloxatoneWHO MedNet
toloxatonaWHO MedNet
toloxatonumWHO MedNet
Synonyms  Source
rac-toloxatoneChEBI
racemic toloxatoneChEBI
(RS)-toloxatoneChEBI
(5RS)-5-(hydroxymethyl)-3-(3-methylphenyl)-1,3-oxazolidin-2-oneChEBI
rac-5-(hydroxymethyl)-3-(3-methylphenyl)-2-oxazolidinoneChEBI
rac-5-hydroxymethyl-3-(m-tolyl)-2-oxazolidinoneChEBI
Brand Names  Source
HumorylKEGG DRUG
PerenumChemIDplus
Manual XrefsDatabases
2702DrugCentral
DB09245DrugBank
D02559KEGG DRUG
ToloxatoneWikipedia
US4699782Patent
Registry NumbersSources
Reaxys:527506Reaxys
CAS:29218-27-7ChemIDplus
Citations