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CHEBI:134714 - sacubitril

Default Structure
ChEBI IDCHEBI:134714
ChEBI Namesacubitril
Stars
Last Modified23 February 2017
DownloadsMolfile
FormulaC24H29NO5
Net Charge0
Average Mass411.498
Monoisotopic Mass411.20457
SMILESCCOC(=O)[C@H](C)C[C@@H](Cc1ccc(-c2ccccc2)cc1)NC(=O)CCC(=O)O
InChIInChI=1S/C24H29NO5/c1-3-30-24(29)17(2)15-21(25-22(26)13-14-23(27)28)16-18-9-11-20(12-10-18)19-7-5-4-6-8-19/h4-12,17,21H,3,13-16H2,1-2H3,(H,25,26)(H,27,28)/t17-,21+/m1/s1
InChIKeyPYNXFZCZUAOOQC-UTKZUKDTSA-N
Roles Classification
Biological Role:
antiviral agent  A substance that destroys or inhibits replication of viruses.
Applications:
cardiovascular drug  A drug that affects the rate or intensity of cardiac contraction, blood vessel diameter or blood volume.
antihypertensive agent  Any drug used in the treatment of acute or chronic vascular hypertension regardless of pharmacological mechanism.
ChEBI Ontology
Outgoing Relation(s)
sacubitril (CHEBI:134714) has role antihypertensive agent (CHEBI:35674)
sacubitril (CHEBI:134714) has role antiviral agent (CHEBI:22587)
sacubitril (CHEBI:134714) has role cardiovascular drug (CHEBI:35554)
sacubitril (CHEBI:134714) is a biphenyls (CHEBI:22888)
INN  Source
sacubitriloWHO MedNet
Synonyms  Source
AHU-377ChEMBL
AHU377DrugCentral
SacubitrilChEMBL
sucabitrilDrugCentral
Brand Name  Source
Sacubitril component of entrestoChEMBL
Manual XrefsDatabases
5012DrugCentral
Registry NumbersSources
CAS:149709-62-6DrugCentral
Citations