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CHEBI:134703 - fluciclovine (18F)

ChEBI IDCHEBI:134703
ChEBI Namefluciclovine (18F)
Stars
ASCII Namefluciclovine ((18)F)
DefinitionA member of the class of cyclobutanes that is cyclobutane which carries a carboxy, amino and (18F)fluoro groups at positions 1, 1 and 3, respectively (the 1r,3r-stereoisomer). It is a positron emission tomography (PET) radiotracer for visualizing prostate cancer.
Last Modified15 June 2021
DownloadsMolfile
FormulaC5H8NO2
Net Charge0
Average Mass132.125
Monoisotopic Mass132.05644
SMILESN[C@]1(C(=O)O)C[C@@H]([18F])C1
InChIInChI=1S/C5H8FNO2/c6-3-1-5(7,2-3)4(8)9/h3H,1-2,7H2,(H,8,9)/t3-,5-/i6-1
InChIKeyNTEDWGYJNHZKQW-DGMDOPGDSA-N
Wikipedia
Roles Classification
Chemical Roles:
Bronsted base  A molecular entity capable of accepting a hydron from a donor (Brønsted acid).
Bronsted acid  A molecular entity capable of donating a hydron to an acceptor (Brønsted base).
Applications:
radiopharmaceutical  Any pharmaceutical compound containing a radioisotope.
ChEBI Ontology
Outgoing Relation(s)
fluciclovine (18F) (CHEBI:134703) has role radioactive imaging agent (CHEBI:37336)
fluciclovine (18F) (CHEBI:134703) is a 18F radiopharmaceutical (CHEBI:49127)
fluciclovine (18F) (CHEBI:134703) is a cyclobutanes (CHEBI:156473)
fluciclovine (18F) (CHEBI:134703) is a fluoroamino acid (CHEBI:24068)
fluciclovine (18F) (CHEBI:134703) is a monocarboxylic acid (CHEBI:25384)
fluciclovine (18F) (CHEBI:134703) is a primary amino compound (CHEBI:50994)
fluciclovine (18F) (CHEBI:134703) is a α-amino acid (CHEBI:33704)
IUPAC Name 
(1r,3r)-1-amino-3-(18F)fluorocyclobutanecarboxylic acid
INNs  Source
fluciclovine (18F)WHO MedNet
fluciclovina (18F)WHO MedNet
fluciclovine (18F)WHO MedNet
fluciclovinum (18F)WHO MedNet
Synonyms  Source
GE-148DrugCentral
(18F)FACBCDrugBank
NMK36ChemIDplus
AxuminKEGG DRUG
(1r,3r)-1-amino-3-(18F)fluorocyclobutane-1-carboxylic acidIUPAC
anti-1-amino-3-18F-flurocyclobutane-1-carboxylic acidChemIDplus
Manual XrefsDatabases
5153DrugCentral
DB13146DrugBank
D10860KEGG DRUG
Fluciclovine_(18F)Wikipedia
23313216ChemSpider
US10967077Patent
WO2014023775Patent
EP2793954Patent
GB2561122Patent
WO2011044410Patent
Registry NumbersSources
CAS:222727-39-1ChemIDplus
Citations