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CHEBI:134355 - auraptene
| Formula | C19H22O3 |
| Net Charge | 0 |
| Average Mass | 298.382 |
| Monoisotopic Mass | 298.15689 |
| SMILES | CC(C)=CCC/C(C)=C/COc1ccc2ccc(=O)oc2c1 |
| InChI | InChI=1S/C19H22O3/c1-14(2)5-4-6-15(3)11-12-21-17-9-7-16-8-10-19(20)22-18(16)13-17/h5,7-11,13H,4,6,12H2,1-3H3/b15-11+ |
| InChIKey | RSDDHGSKLOSQFK-RVDMUPIBSA-N |
| Wikipedia |
|---|
| Species of Metabolite | Component | Source | Comments |
|---|---|---|---|
| Citrus junos (ncbitaxon:135197) | fruit (BTO:0000486) | PubMed (25522543) | |
| Rutaceae (ncbitaxon:23513) | fruit (BTO:0000486) | PubMed (27771936) | |
| Citrus trifoliata (ncbitaxon:37690) | fruit (BTO:0000486) | PubMed (23872723) |
| Roles Classification |
|---|
| Chemical Role: | antioxidant A substance that opposes oxidation or inhibits reactions brought about by dioxygen or peroxides. |
| Biological Roles: | gamma-secretase modulator A modulator of γ-secretase, one of the three endopeptidases that are specific for amyloid protein precursor and which have been identified based upon the region of the amyloid protein precursor which they cleave. EC 2.7.11.24 (mitogen-activated protein kinase) inhibitor An EC 2.7.11.* (protein-serine/threonine kinase) inhibitor that interferes with the action of mitogen-activated protein kinase (EC 2.7.11.24). apoptosis inducer Any substance that induces the process of apoptosis (programmed cell death) in multi-celled organisms. PPARalpha agonist A PPAR modulator which activates the peroxisome proliferator-activated receptor-α. plant metabolite Any eukaryotic metabolite produced during a metabolic reaction in plants, the kingdom that include flowering plants, conifers and other gymnosperms. dopaminergic agent A drug used for its effects on dopamine receptors, on the life cycle of dopamine, or on the survival of dopaminergic neurons. |
| Applications: | antineoplastic agent A substance that inhibits or prevents the proliferation of neoplasms. gastrointestinal drug A drug used for its effects on the gastrointestinal system, e.g. controlling gastric acidity, regulating gastrointestinal motility and water flow, and improving digestion. hepatoprotective agent Any compound that is able to prevent damage to the liver. neuroprotective agent Any compound that can be used for the treatment of neurodegenerative disorders. vulnerary A drug used in treating and healing of wounds. dopaminergic agent A drug used for its effects on dopamine receptors, on the life cycle of dopamine, or on the survival of dopaminergic neurons. antihypertensive agent Any drug used in the treatment of acute or chronic vascular hypertension regardless of pharmacological mechanism. |
| ChEBI Ontology |
|---|
| Outgoing Relation(s) |
| auraptene (CHEBI:134355) has functional parent umbelliferone (CHEBI:27510) |
| auraptene (CHEBI:134355) has role antihypertensive agent (CHEBI:35674) |
| auraptene (CHEBI:134355) has role antineoplastic agent (CHEBI:35610) |
| auraptene (CHEBI:134355) has role antioxidant (CHEBI:22586) |
| auraptene (CHEBI:134355) has role apoptosis inducer (CHEBI:68495) |
| auraptene (CHEBI:134355) has role dopaminergic agent (CHEBI:48560) |
| auraptene (CHEBI:134355) has role EC 2.7.11.24 (mitogen-activated protein kinase) inhibitor (CHEBI:79091) |
| auraptene (CHEBI:134355) has role gastrointestinal drug (CHEBI:55324) |
| auraptene (CHEBI:134355) has role hepatoprotective agent (CHEBI:62868) |
| auraptene (CHEBI:134355) has role matrix metalloproteinase inhibitor (CHEBI:50664) |
| auraptene (CHEBI:134355) has role neuroprotective agent (CHEBI:63726) |
| auraptene (CHEBI:134355) has role plant metabolite (CHEBI:76924) |
| auraptene (CHEBI:134355) has role PPARα agonist (CHEBI:70782) |
| auraptene (CHEBI:134355) has role vulnerary (CHEBI:73336) |
| auraptene (CHEBI:134355) has role γ-secretase modulator (CHEBI:48668) |
| auraptene (CHEBI:134355) is a coumarins (CHEBI:23403) |
| auraptene (CHEBI:134355) is a monoterpenoid (CHEBI:25409) |
| IUPAC Name |
|---|
| 7-{[(2E)-3,7-dimethylocta-2,6-dien-1-yl]oxy}-2H-1-benzopyran-2-one |
| Synonyms | Source |
|---|---|
| 7-geranyloxycoumarin | SUBMITTER |
| 7-O-geranylumbelliferone | SUBMITTER |
| (E)-7-((3,7-Dimethylocta-2,6-dien-1-yl)oxy)-2H-chromen-2-one | NIST Chemistry WebBook |
| Citations |
|---|