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CHEBI:133750 - Cutin-1

ChEBI IDCHEBI:133750
ChEBI NameCutin-1
Stars
DefinitionA phosphonium ylide that is 2-(triphenylphosphoranylidene)acetamide in which the nitrogen has been converted to the corresponding carbamoyl derivative. By targeting the β-subunit of fatty acid synthase, it inhibits nuclear envelope expansion and nuclear elongation during the closed mitosis of fission yeast.
Last Modified14 October 2016
SubmitterGareth Owen
DownloadsMolfile
FormulaC21H19N2O2P
Net Charge0
Average Mass362.369
Monoisotopic Mass362.11841
SMILESNC(=O)NC(=O)C=P(c1ccccc1)(c1ccccc1)c1ccccc1
InChIInChI=1S/C21H19N2O2P/c22-21(25)23-20(24)16-26(17-10-4-1-5-11-17,18-12-6-2-7-13-18)19-14-8-3-9-15-19/h1-16H,(H3,22,23,24,25)
InChIKeyHIFJFZSMVLIPEA-UHFFFAOYSA-N
Roles Classification
Biological Role:
EC 2.3.1.85 (fatty acid synthase) inhibitor  An EC 2.3.1.* (acyltransferase transferring other than amino-acyl group) inhibitor that interferes with the action of fatty acid synthase (EC 2.3.1.85), a multi-enzyme protein involved in fatty acid synthesis.
ChEBI Ontology
Outgoing Relation(s)
Cutin-1 (CHEBI:133750) has role EC 2.3.1.85 (fatty acid synthase) inhibitor (CHEBI:71476)
Cutin-1 (CHEBI:133750) is a N-acylurea (CHEBI:74266)
Cutin-1 (CHEBI:133750) is a phosphonium ylide (CHEBI:51154)
IUPAC Names 
N-carbamoyl-2-(triphenylphosphoranylidene)acetamide
2-(triphenyl-λ5-phosphanylidene)acetamide
Synonyms  Source
triphenylphosphonium(carbamoylcarbamoyl)methylylidChEBI
ureidocarbomethylentriphenylphosphoniumylidChEBI
Registry NumbersSources
Reaxys:2765280Reaxys
CAS:53296-08-5ChEBI
Citations