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CHEBI:133246 - tetramethylpyrazine

Default Structure
ChEBI IDCHEBI:133246
ChEBI Nametetramethylpyrazine
Stars
DefinitionA member of the class of pyrazines that is pyrazine in which all four hydrogens have been replaced by methyl groups. An alkaloid extracted from Chuanxiong (Ligusticum wallichii).
Last Modified2 October 2018
Submittersabrina, zfin
DownloadsMolfile
FormulaC8H12N2
Net Charge0
Average Mass136.198
Monoisotopic Mass136.10005
SMILESCc1nc(C)c(C)nc1C
InChIInChI=1S/C8H12N2/c1-5-6(2)10-8(4)7(3)9-5/h1-4H3
InChIKeyFINHMKGKINIASC-UHFFFAOYSA-N
Wikipedia
Species of MetaboliteComponentSourceComments
Corynebacterium glutamicum (ncbitaxon:1718) - Article (European Journal of Organic Chemistry, 2010 , 2687-2695)
Ephedra sinica (ncbitaxon:33152) - PubMed (24333010)
Ligusticum wallichii (IPNI:844646-1) - PubMed (25841319)
Roles Classification
Biological Roles:
bacterial metabolite  Any prokaryotic metabolite produced during a metabolic reaction in bacteria.
apoptosis inhibitor  Any substance that inhibits the process of apoptosis (programmed cell death) in multi-celled organisms.
metabolite  Any intermediate or product resulting from metabolism. The term 'metabolite' subsumes the classes commonly known as primary and secondary metabolites.
Applications:
neuroprotective agent  Any compound that can be used for the treatment of neurodegenerative disorders.
antineoplastic agent  A substance that inhibits or prevents the proliferation of neoplasms.
platelet aggregation inhibitor  A drug or agent which antagonizes or impairs any mechanism leading to blood platelet aggregation, whether during the phases of activation and shape change or following the dense-granule release reaction and stimulation of the prostaglandin-thromboxane system.
vasodilator agent  A drug used to cause dilation of the blood vessels.
ChEBI Ontology
Outgoing Relation(s)
tetramethylpyrazine (CHEBI:133246) has role antineoplastic agent (CHEBI:35610)
tetramethylpyrazine (CHEBI:133246) has role apoptosis inhibitor (CHEBI:68494)
tetramethylpyrazine (CHEBI:133246) has role bacterial metabolite (CHEBI:76969)
tetramethylpyrazine (CHEBI:133246) has role neuroprotective agent (CHEBI:63726)
tetramethylpyrazine (CHEBI:133246) has role platelet aggregation inhibitor (CHEBI:50427)
tetramethylpyrazine (CHEBI:133246) has role vasodilator agent (CHEBI:35620)
tetramethylpyrazine (CHEBI:133246) is a alkaloid (CHEBI:22315)
tetramethylpyrazine (CHEBI:133246) is a pyrazines (CHEBI:38314)
IUPAC Name 
tetramethylpyrazine
Synonyms  Source
2,3,5,6,-tetramethyl-1,4-pyrazineMetaCyc
2,3,5,6-tetramethylpyrazineChemIDplus
FEMA 3237ChEBI
FEMA No. 3237ChemIDplus
liqustrazineChemIDplus
TMPSUBMITTER
Manual XrefsDatabases
CPD-15901MetaCyc
HMDB0036584HMDB
TetramethylpyrazineWikipedia
Registry NumbersSources
Reaxys:113100Reaxys
CAS:1124-11-4ChemIDplus
CAS:1124-11-4NIST Chemistry WebBook
Citations