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CHEBI:131843 - meldonium
| Formula | C6H14N2O2 |
| Net Charge | 0 |
| Average Mass | 146.190 |
| Monoisotopic Mass | 146.10553 |
| SMILES | C[N+](C)(C)NCCC(=O)[O-] |
| InChI | InChI=1S/C6H14N2O2/c1-8(2,3)7-5-4-6(9)10/h7H,4-5H2,1-3H3 |
| InChIKey | PVBQYTCFVWZSJK-UHFFFAOYSA-N |
| Wikipedia |
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| Roles Classification |
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| Biological Role: | EC 1.14.11.1 (gamma-butyrobetaine dioxygenase) inhibitor An EC 1.14.11.* (oxidoreductase acting on paired donors, 2-oxoglutarate as one donor, incorporating 1 atom each of oxygen into both donors) inhibitor that interferes with the action of γ-butyrobetaine dioxygenase (EC 1.14.11.1). |
| Applications: | cardiovascular drug A drug that affects the rate or intensity of cardiac contraction, blood vessel diameter or blood volume. neuroprotective agent Any compound that can be used for the treatment of neurodegenerative disorders. cardioprotective agent Any protective agent that is able to prevent damage to the heart. |
| ChEBI Ontology |
|---|
| Outgoing Relation(s) |
| meldonium (CHEBI:131843) has role cardioprotective agent (CHEBI:77307) |
| meldonium (CHEBI:131843) has role cardiovascular drug (CHEBI:35554) |
| meldonium (CHEBI:131843) has role EC 1.14.11.1 (γ-butyrobetaine dioxygenase) inhibitor (CHEBI:131844) |
| meldonium (CHEBI:131843) has role neuroprotective agent (CHEBI:63726) |
| meldonium (CHEBI:131843) is a ammonium betaine (CHEBI:35284) |
| IUPAC Name |
|---|
| 3-(2,2,2-trimethyldiazan-2-ium-1-yl)propanoate |
| INNs | Source |
|---|---|
| meldonio | WHO MedNet |
| meldonium | KEGG DRUG |
| Synonyms | Source |
|---|---|
| 2-(2-carboxyethyl)-1,1,1-trimethyldiazanium | PDBeChem |
| 3-(2,2,2-Trimethyldiazaniumyl)propanoate | ChemIDplus |
| 3-(2,2,2-Trimethylhydrazine)propionate | ChemIDplus |
| MET-88 | ChEMBL |
| mildronate | MetaCyc |
| Quaterine | ChEMBL |
| Citations |
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