EMBL-EBI | Chemical Biology | ChEBI
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| ChEBI ID | CHEBI:131513 |
| ChEBI Name | tranylcypromine hydrochloride |
| Stars | |
| Definition | A racemate comprising equal amounts of (1R,2S)- and (1S,2R)-tranylcypromine hydrochloride. An irreversible monoamine oxidase inhibitor that is used as an antidepressant. |
| Last Modified | 11 March 2016 |
| Submitter | Steve |
| Roles Classification |
|---|
| Biological Roles: | EC 1.4.3.4 (monoamine oxidase) inhibitor An EC 1.4.3.* (oxidoreductase acting on donor CH-NH2 group, oxygen as acceptor) inhibitor that interferes with the action of monoamine oxidase (EC 1.4.3.4). EC 1.14.99.66 (lysine-specific histone demethylase 1A) inhibitor An EC 1.14.99.* (miscellaneous oxidoreductase acting on paired donors, with incorporation or reduction of molecular oxygen) inhibitor that interferes with the action of lysine-specific histone demethylase 1A (EC 1.14.99.66). |
| Applications: | anxiolytic drug Anxiolytic drugs are agents that alleviate anxiety, tension, and anxiety disorders, promote sedation, and have a calming effect without affecting clarity of consciousness or neurologic conditions. antidepressant Antidepressants are mood-stimulating drugs used primarily in the treatment of affective disorders and related conditions. |
| ChEBI Ontology |
|---|
| Outgoing Relation(s) |
| tranylcypromine hydrochloride (CHEBI:131513) has part (1R,2S)-tranylcypromine hydrochloride (CHEBI:131514) |
| tranylcypromine hydrochloride (CHEBI:131513) has part (1S,2R)-tranylcypromine hydrochloride (CHEBI:131516) |
| tranylcypromine hydrochloride (CHEBI:131513) has role antidepressant (CHEBI:35469) |
| tranylcypromine hydrochloride (CHEBI:131513) has role anxiolytic drug (CHEBI:35474) |
| tranylcypromine hydrochloride (CHEBI:131513) has role EC 1.14.99.66 (lysine-specific histone demethylase 1A) inhibitor (CHEBI:131509) |
| tranylcypromine hydrochloride (CHEBI:131513) has role EC 1.4.3.4 (monoamine oxidase) inhibitor (CHEBI:38623) |
| tranylcypromine hydrochloride (CHEBI:131513) is a racemate (CHEBI:60911) |
| IUPAC Names |
|---|
| rac-(1R,2S)-2-phenylcyclopropan-1-aminium chloride |
| rac-(1R,2S)-2-phenylcyclopropan-1-amine hydrochloride |
| Synonyms | Source |
|---|---|
| rac-tranylcypromine hydrochloride | ChEBI |
| trans-2-phenylcyclopropylamine hydrochloride | ChEBI |
| DL-tranylcypromine hydrochloride | ChEBI |
| (1R*,2S*)-2-phenylcyclopropan-1-amine hydrochloride | ChEBI |
| (±)-trans-2-phenylcyclopropylamine hydrochloride | ChEBI |
| Registry Numbers | Sources |
|---|---|
| Reaxys:8220297 | Reaxys |