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CHEBI:12071 - 5,10-methylenetetrahydrofolate(2−)

ChEBI IDCHEBI:12071
ChEBI Name5,10-methylenetetrahydrofolate(2−)
Stars
ASCII Name5,10-methylenetetrahydrofolate(2-)
Last Modified21 January 2016
DownloadsMolfile
FormulaC20H21N7O6
Net Charge-2
Average Mass455.431
Monoisotopic Mass455.15643
SMILESNc1nc2c(c(=O)n1)N1CN(c3ccc(C(=O)N[C@@H](CCC(=O)[O-])C(=O)[O-])cc3)CC1CN2
InChIInChI=1S/C20H23N7O6/c21-20-24-16-15(18(31)25-20)27-9-26(8-12(27)7-22-16)11-3-1-10(2-4-11)17(30)23-13(19(32)33)5-6-14(28)29/h1-4,12-13H,5-9H2,(H,23,30)(H,28,29)(H,32,33)(H4,21,22,24,25,31)/p-2/t12?,13-/m0/s1
InChIKeyQYNUQALWYRSVHF-ABLWVSNPSA-L
Species of MetaboliteComponentSourceComments
Saccharomyces cerevisiae (ncbitaxon:4932) - PubMed (24678285) Source: yeast.sf.net
Roles Classification
Biological Roles:
Saccharomyces cerevisiae metabolite  Any fungal metabolite produced during a metabolic reaction in Baker's yeast (Saccharomyces cerevisiae ).
water-soluble vitamin (role)  Any vitamin that dissolves in water and readily absorbed into tissues for immediate use. Unlike the fat-soluble vitamins, they are not stored in the body and need to be replenished regularly in the diet and will rarely accumulate to toxic levels since they are quickly excreted from the body via urine.
Application:
nutraceutical  A product in capsule, tablet or liquid form that provide essential nutrients, such as a vitamin, an essential mineral, a protein, an herb, or similar nutritional substance.
ChEBI Ontology
Outgoing Relation(s)
5,10-methylenetetrahydrofolate(2−) (CHEBI:12071) has role Saccharomyces cerevisiae metabolite (CHEBI:75772)
5,10-methylenetetrahydrofolate(2−) (CHEBI:12071) is a dicarboxylic acid dianion (CHEBI:28965)
5,10-methylenetetrahydrofolate(2−) (CHEBI:12071) is a tetrahydrofolate (CHEBI:67016)
5,10-methylenetetrahydrofolate(2−) (CHEBI:12071) is conjugate base of 5,10-methylenetetrahydrofolic acid (CHEBI:20502)
Incoming Relation(s)
(6R)-5,10-methylenetetrahydrofolate(2−) (CHEBI:15636) is a 5,10-methylenetetrahydrofolate(2−) (CHEBI:12071)
5,10-methylenetetrahydrofolic acid (CHEBI:20502) is conjugate acid of 5,10-methylenetetrahydrofolate(2−) (CHEBI:12071)
IUPAC Name 
N-{4-[3-amino-1-oxo-1,2,5,6,6a,7-hexahydroimidazo[1,5-f]pteridin-8(9H)-yl]benzoyl}-L-glutamate
UniProt Name  Source
5,10-methylenetetrahydrofolateUniProt