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CHEBI:119486 - efavirenz
| Formula | C14H9ClF3NO2 |
| Net Charge | 0 |
| Average Mass | 315.678 |
| Monoisotopic Mass | 315.02739 |
| SMILES | O=C1Nc2ccc(Cl)cc2[C@@](C#CC2CC2)(C(F)(F)F)O1 |
| InChI | InChI=1S/C14H9ClF3NO2/c15-9-3-4-11-10(7-9)13(14(16,17)18,21-12(20)19-11)6-5-8-1-2-8/h3-4,7-8H,1-2H2,(H,19,20)/t13-/m0/s1 |
| InChIKey | XPOQHMRABVBWPR-ZDUSSCGKSA-N |
| Wikipedia |
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| Roles Classification |
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| Biological Roles: | anti-HIV agent An antiviral agent that destroys or inhibits the replication of the human immunodeficiency virus. antitubercular agent A substance that kills or slows the growth of Mycobacterium tuberculosis and is used in the treatment of tuberculosis. antiviral agent A substance that destroys or inhibits replication of viruses. antiviral drug A substance used in the prophylaxis or therapy of virus diseases. antimalarial A drug used in the treatment of malaria. Antimalarials are usually classified on the basis of their action against Plasmodia at different stages in their life cycle in the human. HIV-1 reverse transcriptase inhibitor An entity which inhibits the activity of HIV-1 reverse transcriptase. |
| Applications: | antitubercular agent A substance that kills or slows the growth of Mycobacterium tuberculosis and is used in the treatment of tuberculosis. antiviral drug A substance used in the prophylaxis or therapy of virus diseases. antineoplastic agent A substance that inhibits or prevents the proliferation of neoplasms. antimalarial A drug used in the treatment of malaria. Antimalarials are usually classified on the basis of their action against Plasmodia at different stages in their life cycle in the human. hypoglycemic agent A drug which lowers the blood glucose level. antiinfective agent A substance used in the prophylaxis or therapy of infectious diseases. |
| ChEBI Ontology |
|---|
| Outgoing Relation(s) |
| efavirenz (CHEBI:119486) has role anti-HIV agent (CHEBI:64946) |
| efavirenz (CHEBI:119486) has role antiinfective agent (CHEBI:35441) |
| efavirenz (CHEBI:119486) has role antimalarial (CHEBI:38068) |
| efavirenz (CHEBI:119486) has role antineoplastic agent (CHEBI:35610) |
| efavirenz (CHEBI:119486) has role antitubercular agent (CHEBI:33231) |
| efavirenz (CHEBI:119486) has role antiviral agent (CHEBI:22587) |
| efavirenz (CHEBI:119486) has role antiviral drug (CHEBI:36044) |
| efavirenz (CHEBI:119486) has role HIV-1 reverse transcriptase inhibitor (CHEBI:53756) |
| efavirenz (CHEBI:119486) has role hypoglycemic agent (CHEBI:35526) |
| efavirenz (CHEBI:119486) is a acetylenic compound (CHEBI:73474) |
| efavirenz (CHEBI:119486) is a benzoxazine (CHEBI:46969) |
| efavirenz (CHEBI:119486) is a cyclopropanes (CHEBI:51454) |
| efavirenz (CHEBI:119486) is a organochlorine compound (CHEBI:36683) |
| efavirenz (CHEBI:119486) is a organofluorine compound (CHEBI:37143) |
| IUPAC Name |
|---|
| (4S)-6-chloro-4-(cyclopropylethynyl)-4-(trifluoromethyl)-1,4-dihydro-2H-3,1-benzoxazin-2-one |
| Synonyms | Source |
|---|---|
| 6-chloro-4-(2-cyclopropyl-1-ethynyl)-4-trifluoromethyl-(4S)-1,4-dihydro-2H-benzo[d][1,3]oxazin-2-one | ChEMBL |
| (-)-6-CHLORO-4-CYCLOPROPYLETHYNYL-4-TRIFLUOROMETHYL-1,4-DIHYDRO-2H-3,1-BENZOXAZIN-2-ONE | PDBeChem |
| DMP-266 | ChEMBL |
| Efavirenz | KEGG COMPOUND |
| Efavirenz teva | ChEMBL |
| Efavirenzum | ChEMBL |
| Brand Names | Source |
|---|---|
| Efavirenz component of atripla | ChEMBL |
| Efavirenz component of symfi | ChEMBL |
| Efavirenz component of telura | ChEMBL |
| Sustiva 600 | ChEMBL |
| Citations |
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