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CHEBI:119486 - efavirenz
| Formula | C14H9ClF3NO2 |
| Net Charge | 0 |
| Average Mass | 315.678 |
| Monoisotopic Mass | 315.02739 |
| SMILES | O=C1Nc2ccc(Cl)cc2[C@@](C#CC2CC2)(C(F)(F)F)O1 |
| InChI | InChI=1S/C14H9ClF3NO2/c15-9-3-4-11-10(7-9)13(14(16,17)18,21-12(20)19-11)6-5-8-1-2-8/h3-4,7-8H,1-2H2,(H,19,20)/t13-/m0/s1 |
| InChIKey | XPOQHMRABVBWPR-ZDUSSCGKSA-N |
| Wikipedia |
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| Roles Classification |
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| Biological Roles: | antiviral agent A substance that destroys or inhibits replication of viruses. HIV-1 reverse transcriptase inhibitor An entity which inhibits the activity of HIV-1 reverse transcriptase. antitubercular agent A substance that kills or slows the growth of Mycobacterium tuberculosis and is used in the treatment of tuberculosis. antiviral drug A substance used in the prophylaxis or therapy of virus diseases. antimalarial A drug used in the treatment of malaria. Antimalarials are usually classified on the basis of their action against Plasmodia at different stages in their life cycle in the human. anti-HIV agent An antiviral agent that destroys or inhibits the replication of the human immunodeficiency virus. |
| Applications: | hypoglycemic agent A drug which lowers the blood glucose level. antiinfective agent A substance used in the prophylaxis or therapy of infectious diseases. antitubercular agent A substance that kills or slows the growth of Mycobacterium tuberculosis and is used in the treatment of tuberculosis. antineoplastic agent A substance that inhibits or prevents the proliferation of neoplasms. antiviral drug A substance used in the prophylaxis or therapy of virus diseases. antimalarial A drug used in the treatment of malaria. Antimalarials are usually classified on the basis of their action against Plasmodia at different stages in their life cycle in the human. |
| ChEBI Ontology |
|---|
| Outgoing Relation(s) |
| efavirenz (CHEBI:119486) has role anti-HIV agent (CHEBI:64946) |
| efavirenz (CHEBI:119486) has role antiinfective agent (CHEBI:35441) |
| efavirenz (CHEBI:119486) has role antimalarial (CHEBI:38068) |
| efavirenz (CHEBI:119486) has role antineoplastic agent (CHEBI:35610) |
| efavirenz (CHEBI:119486) has role antitubercular agent (CHEBI:33231) |
| efavirenz (CHEBI:119486) has role antiviral agent (CHEBI:22587) |
| efavirenz (CHEBI:119486) has role antiviral drug (CHEBI:36044) |
| efavirenz (CHEBI:119486) has role HIV-1 reverse transcriptase inhibitor (CHEBI:53756) |
| efavirenz (CHEBI:119486) has role hypoglycemic agent (CHEBI:35526) |
| efavirenz (CHEBI:119486) is a acetylenic compound (CHEBI:73474) |
| efavirenz (CHEBI:119486) is a benzoxazine (CHEBI:46969) |
| efavirenz (CHEBI:119486) is a cyclopropanes (CHEBI:51454) |
| efavirenz (CHEBI:119486) is a organochlorine compound (CHEBI:36683) |
| efavirenz (CHEBI:119486) is a organofluorine compound (CHEBI:37143) |
| IUPAC Name |
|---|
| (4S)-6-chloro-4-(cyclopropylethynyl)-4-(trifluoromethyl)-1,4-dihydro-2H-3,1-benzoxazin-2-one |
| Synonyms | Source |
|---|---|
| 6-chloro-4-(2-cyclopropyl-1-ethynyl)-4-trifluoromethyl-(4S)-1,4-dihydro-2H-benzo[d][1,3]oxazin-2-one | ChEMBL |
| (-)-6-CHLORO-4-CYCLOPROPYLETHYNYL-4-TRIFLUOROMETHYL-1,4-DIHYDRO-2H-3,1-BENZOXAZIN-2-ONE | PDBeChem |
| DMP-266 | ChEMBL |
| Efavirenz | KEGG COMPOUND |
| Efavirenz teva | ChEMBL |
| Efavirenzum | ChEMBL |
| Brand Names | Source |
|---|---|
| Efavirenz component of atripla | ChEMBL |
| Efavirenz component of symfi | ChEMBL |
| Efavirenz component of telura | ChEMBL |
| Sustiva 600 | ChEMBL |
| Citations |
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