EMBL-EBI | Chemical Biology | ChEBI

Example searches: iron*, InChI=1S/CH4O/c1-2/h2H,1H3, caffeine | Advanced Search

CHEBI:116991 - 7-chloro-5-(4-fluorophenyl)-4-(1-oxopropyl)-3,5-dihydro-1H-1,4-benzodiazepin-2-one

ChEBI IDCHEBI:116991
ChEBI Name7-chloro-5-(4-fluorophenyl)-4-(1-oxopropyl)-3,5-dihydro-1H-1,4-benzodiazepin-2-one
Stars
DownloadsMolfile
FormulaC18H16ClFN2O2
Net Charge0
Average Mass346.789
Monoisotopic Mass346.08843
SMILESCCC(=O)N1CC(=O)Nc2ccc(Cl)cc2C1c1ccc(F)cc1
InChIInChI=1S/C18H16ClFN2O2/c1-2-17(24)22-10-16(23)21-15-8-5-12(19)9-14(15)18(22)11-3-6-13(20)7-4-11/h3-9,18H,2,10H2,1H3,(H,21,23)
InChIKeyUOYNCKOPUNYWCU-UHFFFAOYSA-N
Roles Classification
Biological Role:
GABA modulator  A substance that does not act as agonist or antagonist but does affect the gamma-aminobutyric acid receptor-ionophore complex. GABA-A receptors appear to have at least three allosteric sites at which modulators act: a site at which benzodiazepines act by increasing the opening frequency of gamma-aminobutyric acid-activated chloride channels; a site at which barbiturates act to prolong the duration of channel opening; and a site at which some steroids may act.
Application:
GABA modulator  A substance that does not act as agonist or antagonist but does affect the gamma-aminobutyric acid receptor-ionophore complex. GABA-A receptors appear to have at least three allosteric sites at which modulators act: a site at which benzodiazepines act by increasing the opening frequency of gamma-aminobutyric acid-activated chloride channels; a site at which barbiturates act to prolong the duration of channel opening; and a site at which some steroids may act.
ChEBI Ontology
Outgoing Relation(s)
7-chloro-5-(4-fluorophenyl)-4-(1-oxopropyl)-3,5-dihydro-1H-1,4-benzodiazepin-2-one (CHEBI:116991) is a benzodiazepine (CHEBI:22720)
Manual XrefsDatabases
LSM-28439LINCS