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CHEBI:115491 - 7,8-dimethyl-1-[2-oxo-2-(1-pyrrolidinyl)ethyl]-4-phenyl-3H-1,5-benzodiazepin-2-one

ChEBI IDCHEBI:115491
ChEBI Name7,8-dimethyl-1-[2-oxo-2-(1-pyrrolidinyl)ethyl]-4-phenyl-3H-1,5-benzodiazepin-2-one
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DownloadsMolfile
FormulaC23H25N3O2
Net Charge0
Average Mass375.472
Monoisotopic Mass375.19468
SMILESCc1cc2c(cc1C)N(CC(=O)N1CCCC1)C(=O)CC(c1ccccc1)=N2
InChIInChI=1S/C23H25N3O2/c1-16-12-20-21(13-17(16)2)26(15-23(28)25-10-6-7-11-25)22(27)14-19(24-20)18-8-4-3-5-9-18/h3-5,8-9,12-13H,6-7,10-11,14-15H2,1-2H3
InChIKeyARZQAIDEAJTKDX-UHFFFAOYSA-N
Roles Classification
Biological Role:
GABA modulator  A substance that does not act as agonist or antagonist but does affect the gamma-aminobutyric acid receptor-ionophore complex. GABA-A receptors appear to have at least three allosteric sites at which modulators act: a site at which benzodiazepines act by increasing the opening frequency of gamma-aminobutyric acid-activated chloride channels; a site at which barbiturates act to prolong the duration of channel opening; and a site at which some steroids may act.
Application:
GABA modulator  A substance that does not act as agonist or antagonist but does affect the gamma-aminobutyric acid receptor-ionophore complex. GABA-A receptors appear to have at least three allosteric sites at which modulators act: a site at which benzodiazepines act by increasing the opening frequency of gamma-aminobutyric acid-activated chloride channels; a site at which barbiturates act to prolong the duration of channel opening; and a site at which some steroids may act.
ChEBI Ontology
Outgoing Relation(s)
7,8-dimethyl-1-[2-oxo-2-(1-pyrrolidinyl)ethyl]-4-phenyl-3H-1,5-benzodiazepin-2-one (CHEBI:115491) is a benzodiazepine (CHEBI:22720)
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