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CHEBI:114315 - 4,8-dimethyl-1-(phenylmethyl)-3H-1,5-benzodiazepin-2-one

Default Structure
ChEBI IDCHEBI:114315
ChEBI Name4,8-dimethyl-1-(phenylmethyl)-3H-1,5-benzodiazepin-2-one
Stars
DownloadsMolfile
FormulaC18H18N2O
Net Charge0
Average Mass278.355
Monoisotopic Mass278.14191
SMILESCC1=Nc2ccc(C)cc2N(Cc2ccccc2)C(=O)C1
InChIInChI=1S/C18H18N2O/c1-13-8-9-16-17(10-13)20(18(21)11-14(2)19-16)12-15-6-4-3-5-7-15/h3-10H,11-12H2,1-2H3
InChIKeyKUQWFPDSBDBWKK-UHFFFAOYSA-N
Roles Classification
Biological Role:
GABA modulator  A substance that does not act as agonist or antagonist but does affect the gamma-aminobutyric acid receptor-ionophore complex. GABA-A receptors appear to have at least three allosteric sites at which modulators act: a site at which benzodiazepines act by increasing the opening frequency of gamma-aminobutyric acid-activated chloride channels; a site at which barbiturates act to prolong the duration of channel opening; and a site at which some steroids may act.
Application:
GABA modulator  A substance that does not act as agonist or antagonist but does affect the gamma-aminobutyric acid receptor-ionophore complex. GABA-A receptors appear to have at least three allosteric sites at which modulators act: a site at which benzodiazepines act by increasing the opening frequency of gamma-aminobutyric acid-activated chloride channels; a site at which barbiturates act to prolong the duration of channel opening; and a site at which some steroids may act.
ChEBI Ontology
Outgoing Relation(s)
4,8-dimethyl-1-(phenylmethyl)-3H-1,5-benzodiazepin-2-one (CHEBI:114315) is a benzodiazepine (CHEBI:22720)
Manual XrefsDatabases
LSM-25775LINCS