EMBL-EBI | Chemical Biology | ChEBI

Example searches: iron*, InChI=1S/CH4O/c1-2/h2H,1H3, caffeine | Advanced Search

CHEBI:107194 - 2,4-bis(4-methoxyphenyl)-4-methyl-1,2,3,5-tetrahydro-1,5-benzodiazepine

ChEBI IDCHEBI:107194
ChEBI Name2,4-bis(4-methoxyphenyl)-4-methyl-1,2,3,5-tetrahydro-1,5-benzodiazepine
Stars
DownloadsMolfile
FormulaC24H26N2O2
Net Charge0
Average Mass374.484
Monoisotopic Mass374.19943
SMILESCOc1ccc(C2CC(C)(c3ccc(OC)cc3)Nc3ccccc3N2)cc1
InChIInChI=1S/C24H26N2O2/c1-24(18-10-14-20(28-3)15-11-18)16-23(17-8-12-19(27-2)13-9-17)25-21-6-4-5-7-22(21)26-24/h4-15,23,25-26H,16H2,1-3H3
InChIKeyIWKLXNHIGJNDLO-UHFFFAOYSA-N
Roles Classification
Biological Role:
GABA modulator  A substance that does not act as agonist or antagonist but does affect the gamma-aminobutyric acid receptor-ionophore complex. GABA-A receptors appear to have at least three allosteric sites at which modulators act: a site at which benzodiazepines act by increasing the opening frequency of gamma-aminobutyric acid-activated chloride channels; a site at which barbiturates act to prolong the duration of channel opening; and a site at which some steroids may act.
Application:
GABA modulator  A substance that does not act as agonist or antagonist but does affect the gamma-aminobutyric acid receptor-ionophore complex. GABA-A receptors appear to have at least three allosteric sites at which modulators act: a site at which benzodiazepines act by increasing the opening frequency of gamma-aminobutyric acid-activated chloride channels; a site at which barbiturates act to prolong the duration of channel opening; and a site at which some steroids may act.
ChEBI Ontology
Outgoing Relation(s)
2,4-bis(4-methoxyphenyl)-4-methyl-1,2,3,5-tetrahydro-1,5-benzodiazepine (CHEBI:107194) is a benzodiazepine (CHEBI:22720)
Manual XrefsDatabases
LSM-18548LINCS