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CHEBI:10099 - N-[(benzyloxy)carbonyl]-L-tyrosyl-N-hydroxy-L-leucinamide

ChEBI IDCHEBI:10099
ChEBI NameN-[(benzyloxy)carbonyl]-L-tyrosyl-N-hydroxy-L-leucinamide
Stars
ASCII NameN-[(benzyloxy)carbonyl]-L-tyrosyl-N-hydroxy-L-leucinamide
DefinitionThe dipeptide obtained by coupling N-benzyloxycarbonyl-L-tyrosine with the hydroxamic acid derivative of L-leucine. It is an inhibitor of the metallo-protease enzyme, pseudolysin (EC 3.4.24.36).
Last Modified3 August 2014
DownloadsMolfile
FormulaC23H29N3O6
Net Charge0
Average Mass443.500
Monoisotopic Mass443.20564
SMILESCC(C)C[C@H](NC(=O)[C@H](Cc1ccc(O)cc1)NC(=O)OCc1ccccc1)C(=O)NO
InChIInChI=1S/C23H29N3O6/c1-15(2)12-19(22(29)26-31)24-21(28)20(13-16-8-10-18(27)11-9-16)25-23(30)32-14-17-6-4-3-5-7-17/h3-11,15,19-20,27,31H,12-14H2,1-2H3,(H,24,28)(H,25,30)(H,26,29)/t19-,20-/m0/s1
InChIKeyYBHTVSIBHATTHP-PMACEKPBSA-N
Roles Classification
Chemical Role:
Bronsted base  A molecular entity capable of accepting a hydron from a donor (Brønsted acid).
Biological Role:
EC 3.4.24.* (metalloendopeptidase) inhibitor  Any EC 3.4.* (hydrolases acting on peptide bond) inhibitor that interferes with the activity of a metalloendopeptidase (EC 3.4.24.*).
ChEBI Ontology
Outgoing Relation(s)
N-[(benzyloxy)carbonyl]-L-tyrosyl-N-hydroxy-L-leucinamide (CHEBI:10099) has role EC 3.4.24.* (metalloendopeptidase) inhibitor (CHEBI:59107)
N-[(benzyloxy)carbonyl]-L-tyrosyl-N-hydroxy-L-leucinamide (CHEBI:10099) is a dipeptide (CHEBI:46761)
IUPAC Name 
N-[(benzyloxy)carbonyl]-L-tyrosyl-N-hydroxy-L-leucinamide
Synonyms  Source
Z-Tyr-Leu-NHOHKEGG COMPOUND
Z-L-Tyr-L-Leu-NHOHChEBI
N-[(benzyloxy)carbonyl]-L-tyrosyl-L-leucine hydroxamic acidChEBI
Cbz-Tyr-Leu-NHOHKEGG COMPOUND
Benzyloxycarbonyl-Tyr-Leu-NHOHKEGG COMPOUND
Manual XrefsDatabases
C02203KEGG COMPOUND