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CHEBI:10033 - warfarin
| ChEBI ID | CHEBI:10033 |
| ChEBI Name | warfarin |
| Stars | |
| Definition | A racemate comprising equal amounts of (R)- and (S)-warfarin. Extensively used as both an anticoagulant drug and as a pesticide against rats and mice. |
| Last Modified | 7 November 2023 |
| Formula | C19H16O4 |
| Net Charge | 0 |
| Average Mass | 308.333 |
| Monoisotopic Mass | 308.10486 |
| Wikipedia |
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| Roles Classification |
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| Biological Roles: | EC 1.6.5.2 [NAD(P)H dehydrogenase (quinone)] inhibitor An EC 1.6.5.* (oxidoreductase acting on NADH or NADPH with a quinone or similar as acceptor) inhibitor that interferes with the action of NAD(P)H dehydrogenase (quinone), EC 1.6.5.2. vitamin K antagonist A class of anticoagulants which act by inhibiting the action of vitamin K. |
| Applications: | rodenticide A substance used to destroy rodent pests. anticoagulant An agent that prevents blood clotting. |
| ChEBI Ontology |
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| Outgoing Relation(s) |
| warfarin (CHEBI:10033) has part (R)-warfarin (CHEBI:87737) |
| warfarin (CHEBI:10033) has part (S)-warfarin (CHEBI:87738) |
| warfarin (CHEBI:10033) has role anticoagulant (CHEBI:50249) |
| warfarin (CHEBI:10033) has role EC 1.6.5.2 [NAD(P)H dehydrogenase (quinone)] inhibitor (CHEBI:50390) |
| warfarin (CHEBI:10033) has role rodenticide (CHEBI:33288) |
| warfarin (CHEBI:10033) has role vitamin K antagonist (CHEBI:55347) |
| warfarin (CHEBI:10033) is a racemate (CHEBI:60911) |
| warfarin (CHEBI:10033) is conjugate acid of warfarin(1−) (CHEBI:50393) |
| Incoming Relation(s) |
| warfarin(1−) (CHEBI:50393) is conjugate base of warfarin (CHEBI:10033) |
| IUPAC Name |
|---|
| rac-4-hydroxy-3-(3-oxo-1-phenylbutyl)-2H-1-benzopyran-2-one |
| INNs | Source |
|---|---|
| warfarin | WHO MedNet |
| warfarina | WHO MedNet |
| warfarine | WHO MedNet |
| warfarinum | WHO MedNet |
| Synonyms | Source |
|---|---|
| 4-hydroxy-3-[(1RS)-3-oxo-1-phenylbutyl]-2H-1-benzopyran-2-one | IUPAC |
| 4-hydroxy-3-[(1RS)-3-oxo-1-phenylbutyl]-2H-chromen-2-one | IUPAC |
| 4-hydroxy-3-[(1RS)-3-oxo-1-phenylbutyl]coumarin | PPDB |
| Coumafene | ChemIDplus |
| rac-1-(4'-hydroxy-3'-coumarinyl)-1-phenyl-3-butanone | ChemIDplus |
| rac-3-(1'-phenyl-2'-acetylethyl)-4-hydroxycoumarin | ChemIDplus |
| Brand Names | Source |
|---|---|
| Brumolin | ChEBI |
| Kumadu | ChEBI |
| Kumatox | ChEBI |
| Ratron | ChEBI |
| Rodafarin | ChEBI |
| Warf 10 | DrugBank |
| Citations |
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