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PDBsum entry 2qkr
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* Residue conservation analysis
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PDB id:
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| Name: |
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Transferase
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Title:
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Cryptosporidium parvum cyclin-dependent kinase cgd5_2510 with indirubin 3'-monoxime bound
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Structure:
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Cdc2-like cdk2/cdc28 like protein kinase. Chain: a. Engineered: yes
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Source:
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Cryptosporidium parvum iowa ii. Organism_taxid: 353152. Strain: iowa type ii. Gene: cgd5_2510. Expressed in: escherichia coli. Expression_system_taxid: 562.
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Resolution:
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2.60Å
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R-factor:
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0.249
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R-free:
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0.300
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Authors:
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A.K.Wernimont,A.Dong,J.Lew,Y.H.Lin,A.Hassanali,C.H.Arrowsmith, A.M.Edwards,J.Weigelt,M.Sundstrom,A.Bochkarev,R.Hui,J.D.Artz, Structural Genomics Consortium (Sgc)
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Key ref:
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A.K.Wernimont
et al.
Cryptosporidium parvum cyclin-Dependent kinase cgd5_2510 with indirubin 3'-Monoxime bound..
To be published,
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Date:
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11-Jul-07
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Release date:
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04-Sep-07
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PROCHECK
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Headers
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References
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Q5CRJ8
(Q5CRJ8_CRYPI) -
Cdc2-like CDK2/CDC28 like protein kinase (Fragment) from Cryptosporidium parvum (strain Iowa II)
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Seq: Struc:
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295 a.a.
273 a.a.
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Key: |
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PfamA domain |
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Secondary structure |
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CATH domain |
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Enzyme class:
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E.C.2.7.11.22
- cyclin-dependent kinase.
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Reaction:
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1.
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L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H+
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2.
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L-threonyl-[protein] + ATP = O-phospho-L-threonyl-[protein] + ADP + H+
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L-seryl-[protein]
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+
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ATP
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=
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O-phospho-L-seryl-[protein]
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+
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ADP
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+
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H(+)
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L-threonyl-[protein]
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+
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ATP
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=
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O-phospho-L-threonyl-[protein]
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+
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ADP
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+
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H(+)
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Molecule diagrams generated from .mol files obtained from the
KEGG ftp site
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}
}
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