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PDBsum entry 2qkr

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protein ligands links
Transferase PDB id
2qkr

 

 

 

 

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JSmol PyMol  
Contents
Protein chain
273 a.a. *
Ligands
IXM
Waters ×23
* Residue conservation analysis
PDB id:
2qkr
Name: Transferase
Title: Cryptosporidium parvum cyclin-dependent kinase cgd5_2510 with indirubin 3'-monoxime bound
Structure: Cdc2-like cdk2/cdc28 like protein kinase. Chain: a. Engineered: yes
Source: Cryptosporidium parvum iowa ii. Organism_taxid: 353152. Strain: iowa type ii. Gene: cgd5_2510. Expressed in: escherichia coli. Expression_system_taxid: 562.
Resolution:
2.60Å     R-factor:   0.249     R-free:   0.300
Authors: A.K.Wernimont,A.Dong,J.Lew,Y.H.Lin,A.Hassanali,C.H.Arrowsmith, A.M.Edwards,J.Weigelt,M.Sundstrom,A.Bochkarev,R.Hui,J.D.Artz, Structural Genomics Consortium (Sgc)
Key ref: A.K.Wernimont et al. Cryptosporidium parvum cyclin-Dependent kinase cgd5_2510 with indirubin 3'-Monoxime bound.. To be published, .
Date:
11-Jul-07     Release date:   04-Sep-07    
PROCHECK
Go to PROCHECK summary
 Headers
 References

Protein chain
Pfam   ArchSchema ?
Q5CRJ8  (Q5CRJ8_CRYPI) -  Cdc2-like CDK2/CDC28 like protein kinase (Fragment) from Cryptosporidium parvum (strain Iowa II)
Seq:
Struc:
295 a.a.
273 a.a.
Key:    PfamA domain  Secondary structure  CATH domain

 Enzyme reactions 
   Enzyme class: E.C.2.7.11.22  - cyclin-dependent kinase.
[IntEnz]   [ExPASy]   [KEGG]   [BRENDA]
      Reaction:
1. L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H+
2. L-threonyl-[protein] + ATP = O-phospho-L-threonyl-[protein] + ADP + H+
L-seryl-[protein]
+ ATP
= O-phospho-L-seryl-[protein]
+ ADP
+ H(+)
L-threonyl-[protein]
+ ATP
= O-phospho-L-threonyl-[protein]
+ ADP
+ H(+)
Molecule diagrams generated from .mol files obtained from the KEGG ftp site

 

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