PDBsum entry 1wfw

Signaling protein

PDB id: 1wfw

Contents

Protein chain

74 a.a. *

* Residue conservation analysis

PDB id:

1wfw

Name:

Signaling protein

Title:

Solution structure of sh3 domain of mouse kalirin-9a protein

Structure:

Kalirin-9a. Chain: a. Fragment: sh3 domain. Synonym: unnamed protein product. Engineered: yes. Mutation: yes

Source:

Mus musculus. House mouse. Organism_taxid: 10090. Gene: riken cdna 2210407g14. Other_details: cell-free protein synthesis

NMR struc:

20 models

Authors:

N.Tochio,S.Koshiba,M.Inoue,T.Kigawa,S.Yokoyama,Riken Structural Genomics/proteomics Initiative (Rsgi)

Key ref:

N.Tochio et al. Solution structure of sh3 domain of mouse kalirin-9a protein. To be published, .

Date:

27-May-04 Release date: 27-Nov-04

Protein chain

A2CG49  (KALRN_MOUSE) -  Kalirin from Mus musculus

Seq: 2964 a.a.

Struc: 74 a.a.*

* PDB and UniProt seqs differ at 12 residue positions (black crosses)

Enzyme reactions

• Enzyme class: E.C.2.7.11.1 - non-specific serine/threonine protein kinase.
• Reaction:
  1. L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H⁺
  2. L-threonyl-[protein] + ATP = O-phospho-L-threonyl-[protein] + ADP + H⁺

Molecule diagrams generated from .mol files obtained from the KEGG ftp site