 |
PDBsum entry 1vw3
|
|
|
|
|
 |
Contents |
 |
|
|
|
|
|
|
|
|
|
|
|
295 a.a.
|
|
|
|
|
|
|
|
|
|
|
249 a.a.
|
|
|
|
|
|
|
|
|
|
|
239 a.a.
|
|
|
|
|
|
|
|
|
|
|
|
|
|
References listed in PDB file
|
|
|
Key reference
|
|
|
Title
|
|
Structure of the yeast mitochondrial large ribosomal subunit.
|
|
|
Authors
|
|
A.Amunts,
A.Brown,
X.C.Bai,
J.L.Llácer,
T.Hussain,
P.Emsley,
F.Long,
G.Murshudov,
S.H.Scheres,
V.Ramakrishnan.
|
|
|
Ref.
|
|
Science, 2014,
343,
1485-1489.
[DOI no: ]
|
|
|
PubMed id
|
|
|
|
|
|
Abstract
|
|
|
Mitochondria have specialized ribosomes that have diverged from their bacterial
and cytoplasmic counterparts. We have solved the structure of the yeast
mitoribosomal large subunit using single-particle cryo-electron microscopy. The
resolution of 3.2 angstroms enabled a nearly complete atomic model to be built
de novo and refined, including 39 proteins, 13 of which are unique to
mitochondria, as well as expansion segments of mitoribosomal RNA. The structure
reveals a new exit tunnel path and architecture, unique elements of the E site,
and a putative membrane docking site.
|
|
|
|
|
|
|
