Ligand clusters for UniProt code Q8N5Z0

Ligand clusters for Q8N5Z0: Kynurenine/alpha-aminoadipate aminotransferase, mitochondrial from Homo sapiens

		Top 6 (of 11) ligand clusters Cluster 1. 13 ligand types 13 ligands Cluster 2. 13 ligand types 13 ligands Cluster 3. 1 ligand type 1 ligand Cluster 4. 1 ligand type 1 ligand Cluster 5. 1 ligand type 1 ligand Cluster 6. 1 ligand type 1 ligand
Representative protein: 4ge7A

Structures

PDB		Schematic diagram
4ge7A
6t8qA
2vgzA
6t8pA
4ge9A
		more ...

Cluster 1 contains 13 ligand types

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Ligand		Description
		1. Ligand: GOL × 1 glycerin Glycerol PDB code: 3dc1(A).
		2. Ligand: PLP × 1 pyridoxal phosphate Pyridoxal-5'-Phosphate PDB code: 2vgz(A).
		3. Ligand: 09M × 1 (5-Hydroxy-4-{[(1-Hydroxy-2-Oxo-1,2-Dihydroquinolin-3- Yl)amino]methyl}-6-Methylpyridin-3- Yl)methyl dihydrogen phosphate PDB code: 3ue8(A).
		4. Ligand: 0K5 × 1 (5-Hydroxy-4-{[(1-Hydroxy-2-Oxo-6-Phenoxy-1,2- Dihydroquinolin-3-Yl)amino]methyl}-6-Methylpyridin- 3- Yl)methyl dihydrogen phosphate PDB code: 4ge7(A).
		5. Ligand: 0KE × 1 (5-Hydroxy-4-{[(1-Hydroxy-7-Methoxy-2-Oxo-1,2- Dihydroquinolin-3-Yl)amino]methyl}-6-Methylpyridin- 3- Yl)methyl dihydrogen phosphate PDB code: 4ge4(A).
		6. Ligand: 0L0 × 1 (4-{[(6-Benzyl-1-Hydroxy-7-Methoxy-2-Oxo-1,2- Dihydroquinolin-3-Yl)amino]methyl}-5-Hydroxy-6- Methylpyridin-3-Yl)methyl dihydrogen phosphate PDB code: 4ge9(A).
		7. Ligand: 0LD × 1 (5-Hydroxy-4-{[(7-Hydroxy-6-Oxo-2-Phenyl-6,7-Dihydro- 2h-Pyrazolo[3,4-B]pyridin-5-Yl)amino]methyl}- 6- Methylpyridin-3-Yl)methyl dihydrogen phosphate PDB code: 4geb(A).
		8. Ligand: 0X1 × 1 (5-Hydroxy-6-Methyl-4-{[(1-Oxo-7-Phenoxy-1,2-Dihydro[1, 2,4]triazolo[4,3-A]quinolin-4- Yl)amino]methyl}pyridin- 3-Yl)methyl dihydrogen phosphate PDB code: 4gdy(A).
		9. Ligand: BF5-PLP × 1 BF5=(3s)-10-(4-Aminopiperazin-1-Yl)-9-Fluoro-7- Hydroxy-3-Methyl-2,3-Dihydro-8h-[1,4]oxazino[2, 3,4- Ij]quinoline-6-Carboxylate, PLP=Pyridoxal-5'-Phosphate. PDB code: 2xh1(A).
		10. Ligand: KYN × 1 (2s)-2-Amino-4-(2-Aminophenyl)-4-Oxobutanoic acid PDB code: 2r2n(A).
		11. Ligand: MVQ × 1 (2~{r})-1-[6-Methyl-5-(Oxan-4-Yl)-7-Oxidanylidene-[1, 3]thiazolo[5,4-D]pyrimidin-2-Yl]-~{N}- (Phenylmethyl) pyrrolidine-2-Carboxamide PDB code: 6t8q(A).
		12. Ligand: MVT × 1 3,5-Bis(fluoranyl)-~{N}-[5-[(2~{r})-2-(3-Fluorophenyl)- 3-Methyl-Butyl]-1,3,4-Thiadiazol-2- Yl]benzenesulfonamide PDB code: 6t8p(A).
		13. Ligand: PMP × 1 4'-Deoxy-4'-Aminopyridoxal-5'-Phosphate PDB code: 2r2n(A).

Cluster 2 contains 13 ligand types

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Ligand		Description
		1. Ligand: PLP × 1 pyridoxal phosphate Pyridoxal-5'-Phosphate PDB code: 2vgz(A).
		2. Ligand: 09M × 1 (5-Hydroxy-4-{[(1-Hydroxy-2-Oxo-1,2-Dihydroquinolin-3- Yl)amino]methyl}-6-Methylpyridin-3- Yl)methyl dihydrogen phosphate PDB code: 3ue8(A).
		3. Ligand: 0K5 × 1 (5-Hydroxy-4-{[(1-Hydroxy-2-Oxo-6-Phenoxy-1,2- Dihydroquinolin-3-Yl)amino]methyl}-6-Methylpyridin- 3- Yl)methyl dihydrogen phosphate PDB code: 4ge7(A).
		4. Ligand: 0KE × 1 (5-Hydroxy-4-{[(1-Hydroxy-7-Methoxy-2-Oxo-1,2- Dihydroquinolin-3-Yl)amino]methyl}-6-Methylpyridin- 3- Yl)methyl dihydrogen phosphate PDB code: 4ge4(A).
		5. Ligand: 0L0 × 1 (4-{[(6-Benzyl-1-Hydroxy-7-Methoxy-2-Oxo-1,2- Dihydroquinolin-3-Yl)amino]methyl}-5-Hydroxy-6- Methylpyridin-3-Yl)methyl dihydrogen phosphate PDB code: 4ge9(A).
		6. Ligand: 0LD × 1 (5-Hydroxy-4-{[(7-Hydroxy-6-Oxo-2-Phenyl-6,7-Dihydro- 2h-Pyrazolo[3,4-B]pyridin-5-Yl)amino]methyl}- 6- Methylpyridin-3-Yl)methyl dihydrogen phosphate PDB code: 4geb(A).
		7. Ligand: 0X1 × 1 (5-Hydroxy-6-Methyl-4-{[(1-Oxo-7-Phenoxy-1,2-Dihydro[1, 2,4]triazolo[4,3-A]quinolin-4- Yl)amino]methyl}pyridin- 3-Yl)methyl dihydrogen phosphate PDB code: 4gdy(A).
		8. Ligand: 7AR × 1 (2r)-2-(5,6-Dichloro-1,3-Dioxo-1,3-Dihydro-2h-Isoindol- 2-Yl)-3-Phenylpropanoic acid PDB code: 5tf5(A).
		9. Ligand: AKG × 1 2-Oxoglutaric acid PDB code: 3dc1(A).
		10. Ligand: BF5-PLP × 1 BF5=(3s)-10-(4-Aminopiperazin-1-Yl)-9-Fluoro-7- Hydroxy-3-Methyl-2,3-Dihydro-8h-[1,4]oxazino[2, 3,4- Ij]quinoline-6-Carboxylate, PLP=Pyridoxal-5'-Phosphate. PDB code: 2xh1(A).
		11. Ligand: KYN × 1 (2s)-2-Amino-4-(2-Aminophenyl)-4-Oxobutanoic acid PDB code: 2r2n(A).
		12. Ligand: MVT × 1 3,5-Bis(fluoranyl)-~{N}-[5-[(2~{r})-2-(3-Fluorophenyl)- 3-Methyl-Butyl]-1,3,4-Thiadiazol-2- Yl]benzenesulfonamide PDB code: 6t8p(A).
		13. Ligand: PMP × 1 4'-Deoxy-4'-Aminopyridoxal-5'-Phosphate PDB code: 2r2n(A).

Cluster 3 contains 1 ligand type

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Ligand		Description
		1. Ligand: MVT × 1 3,5-Bis(fluoranyl)-~{N}-[5-[(2~{r})-2-(3-Fluorophenyl)- 3-Methyl-Butyl]-1,3,4-Thiadiazol-2- Yl]benzenesulfonamide PDB code: 6t8p(A).

Cluster 4 contains 1 ligand type

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Ligand		Description
		1. Ligand: GOL × 1 glycerin Glycerol PDB code: 2qlr(A).

Cluster 5 contains 1 ligand type

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Ligand		Description
		1. Ligand: GOL × 1 glycerin Glycerol PDB code: 2qlr(A).

Cluster 6 contains 1 ligand type

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Ligand		Description
		1. Ligand: GOL × 1 glycerin Glycerol PDB code: 2r2n(A).