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Ligand clusters for UniProt code P31749

Ligand clusters for P31749: RAC-alpha serine/threonine-protein kinase from Homo sapiens

Top 6 (of 7) ligand clusters


Cluster 1. 29 ligand types 45 ligands		Cluster 2. 1 ligand type 1 ligand		Cluster 3. 2 ligand types 2 ligands		Cluster 4. 1 ligand type 1 ligand		Cluster 5. 1 ligand type 1 ligand		Cluster 6. 1 ligand type 2 ligands

Representative protein: 6s9wA

Structures

PDB		Schematic diagram

6s9wA
6hhiA
6hhjA
6s9xA
6hhhA
		more ...

Cluster 1 contains 29 ligand types (of which only 20 are listed. Click for all)

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Ligand

Description

_Mn

1. Metal: _MN × 5

PDB codes: 4ekk(A), 6buu(A), 6c0i(A), 6npz(A).

2. Ligand: GOL × 3

glycerin

Glycerol

PDB codes: 4gv1(A),

3. Ligand: GVF × 1

Benzene-1,2,3,4-Tetrayl tetrakis[dihydrogen (phosphate)]

PDB code: 2uvm(A).

4. Ligand: GLY-ARG-PRO-ARG-THR-THR-SER-PHE-ALA-GLU × 9

PDB codes: 3cqu(A), 3cqw(A), 3mv5(A), 3mvh(A), 3ocb(A), 3ow4(A), 3qkk(A), 3qkl(A), 4ekk(A).

5. Ligand: GLY-ARG-PRO-ARG-THR-THR-ZXW-PHE-ALA-GLU × 3

ZXW=5'-O-[(S)-{[(R)-{[(R)-[(2-{[(2s)-2-Amino-3- Oxopropyl]amino}-2-
Oxoethyl)sulfanyl](hydroxy) phosphoryl]oxy}(hydroxy)phosphoryl]oxy}(hydroxy) phosphoryl]adenosine.

PDB codes: 6buu(A), 6c0i(A), 6npz(A).

6. Ligand: 0R4 × 1

N-(4-{5-[3-(Acetylamino)phenyl]-2-(2-Aminopyridin-3- Yl)-3h-Imidazo[4,5-B]pyridin-3-Yl}benzyl)-3-
Fluorobenzamide

PDB code: 4ejn(A).

7. Ligand: 0RF × 1

(2s)-2-(4-Chlorophenyl)-1-{4-[(5r,7r)-7-Hydroxy-5- Methyl-6,7-Dihydro-5h-Cyclopenta[d]pyrimidin-4-
Yl]piperazin-1-Yl}-3-(Propan-2-Ylamino)propan-1-One

PDB code: 4ekl(A).

8. Ligand: 0XZ × 1

4-Amino-N-[(1s)-1-(4-Chlorophenyl)-3-Hydroxypropyl]-1- (7h-Pyrrolo[2,3-D]pyrimidin-4-Yl)piperidine-
4- Carboxamide

PDB code: 4gv1(A).

9. Ligand: 6S1 × 1

3-[3-[4-(1-Azanylcyclobutyl)phenyl]-5-Phenyl-Imidazo[4, 5-B]pyridin-2-Yl]pyridin-2-Amine

PDB code: 5kcv(A).

10. Ligand: ANP × 1

Phosphoaminophosphonic acid-Adenylate ester

PDB code: 4ekk(A).

11. Ligand: CQU × 1

N-[2-(5-Methyl-4h-1,2,4-Triazol-3-Yl)phenyl]-7h- Pyrrolo[2,3-D]pyrimidin-4-Amine

PDB code: 3cqu(A).

12. Ligand: CQW × 1

5-(5-Chloro-7h-Pyrrolo[2,3-D]pyrimidin-4-Yl)-4,5,6,7- Tetrahydro-1h-Imidazo[4,5-C]pyridine

PDB code: 3cqw(A).

13. Ligand: EX4 × 1

(5r)-4-(4-{4-[4-Fluoro-3-(Trifluoromethyl)phenyl]-1-[2- (Pyrrolidin-1-Yl)ethyl]-1h-Imidazol-2-
Yl}piperidin-1- Yl)-5-Methyl-5,8-Dihydropyrido[2,3-D]pyrimidin-7(6h)- One

PDB code: 6ccy(A).

14. Ligand: G4H × 1

~{N}-[1-Methyl-2-Oxidanylidene-3-[1-[[4-(5- Oxidanylidene-3-Phenyl-6~{h}-1,6-Naphthyridin-2-
Yl) phenyl]methyl]piperidin-4-Yl]benzimidazol-5- Yl]propanamide

PDB code: 6hhj(A).

15. Ligand: G4K × 1

Borussertib

PDB code: 6hhf(A).

16. Ligand: G4N × 1

~{N}-[1-[[4-(5-Oxidanylidene-3-Phenyl-6~{h}-1,6- Naphthyridin-2-Yl)phenyl]methyl]piperidin-4-Yl]-3-
(Propanoylamino)benzamide

PDB code: 6hhi(A).

17. Ligand: G4Q × 1

~{N}-[4-[4-[[4-(5-Oxidanylidene-3-Phenyl-6~{h}-1,6- Naphthyridin-2-Yl)phenyl]methyl]piperazin-1-
Yl]phenyl]propanamide

PDB code: 6hhh(A).

18. Ligand: G4T × 1

~{N}-[2-Chloranyl-5-[[1-[[4-(5-Oxidanylidene-3-Phenyl- 6~{h}-1,6-Naphthyridin-2-
Yl)phenyl]methyl]piperidin-4- Yl]carbamoylamino]phenyl]propanamide

PDB code: 6hhg(A).

19. Ligand: IQO × 1

1-(1-(4-(7-Phenyl-1h-Imidazo[4,5-G]quinoxalin-6-Yl) benzyl)piperidin-4-Yl)-1h-Benzo[d]imidazol-
2(3h)-One

PDB code: 3o96(A).

20. Ligand: L1W × 1

~{N}-[3-[1-[[4-[5-[(4-Hydroxyphenyl)methyl]-6- Oxidanylidene-2-Phenyl-1~{h}-Pyrazin-3-
Yl]phenyl]methyl]piperidin-4-Yl]-2-Oxidanylidene- 1~{h}-Benzimidazol-5-Yl]propanamide

PDB code: 6s9x(A).

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