Ligand clusters for UniProt code P00451

Ligand clusters for P00451: Coagulation factor VIII from Homo sapiens

		Top 6 (of 17) ligand clusters Cluster 1. 9 ligand types 11 ligands Cluster 2. 5 ligand types 9 ligands Cluster 3. 3 ligand types 8 ligands Cluster 4. 1 ligand type 1 ligand Cluster 5. 1 ligand type 1 ligand Cluster 6. 1 ligand type 1 ligand
Representative protein: 7k66A

Structures

PDB		Schematic diagram
7k66A
7kbtA
6mf2A
6mf0A
4bdvA
		more ...

Cluster 1 contains 9 ligand types

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Ligand		Description
		1. Ligand: NAG × 1 n-acetylglucosamine 2-Acetamido-2-Deoxy-Beta-D-Glucopyranose PDB code: 3cdz(B).
		2. Ligand: NAG-NAG-BMA-BMA-MAN-MAN-MAN × 2 NAG=2-Acetamido-2-Deoxy-Beta-D-Glucopyranose, BMA=Beta-D-Mannopyranose, MAN=Alpha-D-Mannopyranose. PDB codes: 2r7e(B), 5k8d(B).
		3. Ligand: NAG-NAG-BMA-MAN-MAN × 2 NAG=2-Acetamido-2-Deoxy-Beta-D-Glucopyranose, BMA=Beta-D-Mannopyranose, MAN=Alpha-D-Mannopyranose. PDB codes: 6mf0(A), 7k66(A).
		4. Ligand: EDO × 1 1,2-Ethanediol PDB code: 4bdv(B).
		5. Ligand: NAG-BMA-MAN-BMA × 1 NAG=2-Acetamido-2-Deoxy-Beta-D-Glucopyranose, BMA=Beta-D-Mannopyranose, MAN=Alpha-D-Mannopyranose. PDB code: 3j2q(B).
		6. Ligand: NAG-MAN-MAN-MAN × 1 NAG=2-Acetamido-2-Deoxy-Beta-D-Glucopyranose, MAN=Alpha-D-Mannopyranose. PDB code: 3cdz(B).
		7. Ligand: NAG-NAG × 1 NAG=2-Acetamido-2-Deoxy-Beta-D-Glucopyranose. PDB code: 7kbt(A).
		8. Ligand: NAG-NAG-BMA × 1 NAG=2-Acetamido-2-Deoxy-Beta-D-Glucopyranose, BMA=Beta-D-Mannopyranose. PDB code: 6mf2(A).
		9. Ligand: NAG-NAG-BMA-BMA-BMA × 1 NAG=2-Acetamido-2-Deoxy-Beta-D-Glucopyranose, BMA=Beta-D-Mannopyranose. PDB code: 4bdv(B).

Cluster 2 contains 5 ligand types

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Ligand		Description
		1. Ligand: NAG × 1 n-acetylglucosamine 2-Acetamido-2-Deoxy-Beta-D-Glucopyranose PDB code: 7k66(A).
		2. Ligand: NAG-NAG × 4 NAG=2-Acetamido-2-Deoxy-Beta-D-Glucopyranose. PDB codes: 3cdz(A), 3j2q(A), 4bdv(A), 7kbt(A).
		3. Ligand: NAG-NAG-BMA-MAN × 2 NAG=2-Acetamido-2-Deoxy-Beta-D-Glucopyranose, BMA=Beta-D-Mannopyranose, MAN=Alpha-D-Mannopyranose. PDB codes: 2r7e(A), 5k8d(A).
		4. Ligand: NAG-NAG-BMA × 1 NAG=2-Acetamido-2-Deoxy-Beta-D-Glucopyranose, BMA=Beta-D-Mannopyranose. PDB code: 6mf2(A).
		5. Ligand: NAG-NAG-BMA-MAN-MAN × 1 NAG=2-Acetamido-2-Deoxy-Beta-D-Glucopyranose, BMA=Beta-D-Mannopyranose, MAN=Alpha-D-Mannopyranose. PDB code: 6mf0(A).

Cluster 3 contains 3 ligand types

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Ligand		Description
		1. Ligand: NAG × 3 n-acetylglucosamine 2-Acetamido-2-Deoxy-Beta-D-Glucopyranose PDB codes: 3cdz(B), 3j2q(B), 7kbt(A).
		2. Ligand: NAG-NAG × 3 NAG=2-Acetamido-2-Deoxy-Beta-D-Glucopyranose. PDB codes: 2r7e(B), 5k8d(B), 7k66(A).
		3. Ligand: NAG-NAG-BMA × 2 NAG=2-Acetamido-2-Deoxy-Beta-D-Glucopyranose, BMA=Beta-D-Mannopyranose. PDB codes: 6mf0(A), 6mf2(A).

Cluster 4 contains 1 ligand type

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Ligand		Description
		1. Ligand: 768 × 1 (2r)-1-(2,4-Dichlorophenoxy)-3-[(2e)-2-Imino-3-(2- Piperidin-1-Ylethyl)-2,3-Dihydro-1h- Benzimidazol-1- Yl]propan-2-Ol PDB code: 3hnb(M).

Cluster 5 contains 1 ligand type

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Ligand		Description
		1. Ligand: NAG × 1 n-acetylglucosamine 2-Acetamido-2-Deoxy-Beta-D-Glucopyranose PDB code: 3j2q(A).

Cluster 6 contains 1 ligand type

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Ligand		Description
		1. Ligand: NAG × 1 n-acetylglucosamine 2-Acetamido-2-Deoxy-Beta-D-Glucopyranose PDB code: 3j2q(B).