PDBsum entry 6hdl

Isomerase

PDB id: 6hdl

Contents

Protein chain

219 a.a.

Ligands

BG6

MGF

EDO ×2

Metals

_NA

_MG

Waters ×278

PDB id:

6hdl

Name:

Isomerase

Title:

R49k variant of beta-phosphoglucomutase from lactococcus lactis complexed with magnesium trifluoride and beta-g6p to 1.2 a.

Structure:

Beta-phosphoglucomutase. Chain: a. Synonym: beta-pgm. Engineered: yes. Mutation: yes

Source:

Lactococcus lactis subsp. Lactis. Streptococcus lactis. Organism_taxid: 272623. Strain: il1403. Gene: pgmb, ll0429, l0001. Expressed in: escherichia coli bl21(de3). Expression_system_taxid: 469008

Resolution:

1.16Å R-factor: 0.134 R-free: 0.164

Authors:

H.P.Wood,A.J.Robertson,C.Bisson,J.P.Waltho

Key ref:

A.J.Robertson et al. Transition state of phospho-Enzyme hydrolysis in beta-Phosphoglucomutase.. To be published, .

Date:

17-Aug-18 Release date: 26-Aug-20

Protein chain

P71447  (PGMB_LACLA) -  Beta-phosphoglucomutase from Lactococcus lactis subsp. lactis (strain IL1403)

Seq: 221 a.a.

Struc: 219 a.a.*

* PDB and UniProt seqs differ at 3 residue positions (black crosses)

Enzyme reactions

• Enzyme class: E.C.5.4.2.6 - beta-phosphoglucomutase.
• Pathway: b-phosphoglucomutase
• Reaction: beta-D-glucose 1-phosphate = beta-D-glucose 6-phosphate

beta-D-glucose 1-phosphate = beta-D-glucose 6-phosphate (Bound ligand (Het Group name = BG6) corresponds exactly)

Molecule diagrams generated from .mol files obtained from the KEGG ftp site