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PDBsum entry 4ger

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protein ligands metals links
Hydrolase PDB id
4ger
Jmol
Contents
Protein chains
304 a.a.
Ligands
THR-LYS ×2
Metals
_ZN ×2
_CA ×6
Waters ×612
PDB id:
4ger
Name: Hydrolase
Title: Crystal structure of gentlyase, the neutral metalloprotease paenibacillus polymyxa
Structure: Gentlyase metalloprotease. Chain: a, b. Engineered: yes
Source: Paenibacillus polymyxa. Organism_taxid: 1406. Expressed in: bacillus amyloliquefaciens. Expression_system_taxid: 1390
Resolution:
1.59Å     R-factor:   0.202     R-free:   0.243
Authors: A.Ruf,M.Stihle,J.Benz,M.Schmidt,H.Sobek
Key ref: A.Ruf et al. (2013). Structure of gentlyase, the neutral metalloprotease of Paenibacillus polymyxa. Acta Crystallogr D Biol Crystallogr, 69, 24-31. PubMed id: 23275160
Date:
02-Aug-12     Release date:   02-Jan-13    
PROCHECK
Go to PROCHECK summary
 Headers
 References

Protein chains
Pfam   ArchSchema ?
P29148  (NPRE_PAEPO) -  Bacillolysin
Seq:
Struc:
 
Seq:
Struc:
590 a.a.
304 a.a.*
Key:    PfamA domain  PfamB domain  Secondary structure  CATH domain
* PDB and UniProt seqs differ at 12 residue positions (black crosses)

 Enzyme reactions 
   Enzyme class: E.C.3.4.24.28  - Bacillolysin.
[IntEnz]   [ExPASy]   [KEGG]   [BRENDA]
      Reaction: Similar, but not identical, to that of thermolysin.
      Cofactor: Calcium; Zinc
 Gene Ontology (GO) functional annotation 
  GO annot!
  Biological process     proteolysis   1 term 
  Biochemical function     metalloendopeptidase activity     1 term  

 

 
Acta Crystallogr D Biol Crystallogr 69:24-31 (2013)
PubMed id: 23275160  
 
 
Structure of gentlyase, the neutral metalloprotease of Paenibacillus polymyxa.
A.Ruf, M.Stihle, J.Benz, M.Schmidt, H.Sobek.
 
  ABSTRACT  
 
No abstract given.