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PDBsum entry 3n4m

Go to PDB code: 
protein dna_rna ligands Protein-protein interface(s) links
Gene regulation/DNA PDB id
3n4m
Jmol
Contents
Protein chains
203 a.a.
74 a.a.
DNA/RNA
Ligands
CMP ×2
PEG ×2
Waters ×35
PDB id:
3n4m
Name: Gene regulation/DNA
Title: E. Coli RNA polymerase alpha subunit c-terminal domain in co cap and DNA
Structure: Catabolite gene activator. Chain: a. Synonym: camp receptor protein, camp regulatory protein. Engineered: yes. DNA-directed RNA polymerase subunit alpha. Chain: b, c. Fragment: alpha subunit c-terminal domain, residues 246-329 synonym: rnap subunit alpha, transcriptase subunit alpha, r polymerase subunit alpha.
Source: Escherichia coli. Organism_taxid: 83333. Strain: k12. Gene: b3357, cap, crp, csm, jw5702. Expressed in: escherichia coli. Expression_system_taxid: 562. Gene: b3295, jw3257, pez, phs, rpoa, sez. Synthetic: yes. Synthetic: yes
Resolution:
2.99Å     R-factor:   0.199     R-free:   0.224
Authors: S.Lara-Gonzalez,J.J.Birktoft,C.L.Lawson
Key ref: S.Lara-Gonzalez et al. Combined structural model for a transcription activat assembly. To be published, .
Date:
21-May-10     Release date:   25-May-11    
PROCHECK
Go to PROCHECK summary
 Headers
 References

Protein chain
Pfam   ArchSchema ?
P0ACJ8  (CRP_ECOLI) -  cAMP-activated global transcriptional regulator CRP
Seq:
Struc:
210 a.a.
203 a.a.
Protein chains
Pfam   ArchSchema ?
P0A7Z4  (RPOA_ECOLI) -  DNA-directed RNA polymerase subunit alpha
Seq:
Struc:
329 a.a.
74 a.a.
Key:    PfamA domain  Secondary structure  CATH domain

 Enzyme reactions 
   Enzyme class: Chains B, C: E.C.2.7.7.6  - DNA-directed Rna polymerase.
[IntEnz]   [ExPASy]   [KEGG]   [BRENDA]
      Reaction: Nucleoside triphosphate + RNA(n) = diphosphate + RNA(n+1)
Nucleoside triphosphate
+ RNA(n)
= diphosphate
+ RNA(n+1)
Molecule diagrams generated from .mol files obtained from the KEGG ftp site
 Gene Ontology (GO) functional annotation 
  GO annot!
  Cellular component     intracellular   1 term 
  Biological process     transcription, DNA-dependent   5 terms 
  Biochemical function     nucleotide binding     6 terms