The UniProt Protein DAS Server
The distributed annotation system (DAS) is a client-server system in which a single client
integrates information from multiple servers. The UniProt DAS server provides access to
sequence and annotation from UniProtKB and UniParc. The server also gives access to Gene
Ontology Annotation of UniProt sequences (GOA) and theoretical tryptic digests of protein
sequences. Researchers can easily access DAS data through the use of suitable DAS client such
as Dasty3 or directly in the XML format provided by
the servers.
An extremely useful resource for users of DAS is the DAS
Registration Server that supports registry and discovery of DAS services. The data sources
provided by the UniProt DAS server are all registered with this service.
Access the UniProt DAS Server
Data sources can be accessed here
The UniProt DAS server is built upon the MyDas Java DAS Server Framework. The primary sources of the data available from the UniProt DAS reference server include: UniProtKB/Swiss-Prot, UniProtKB/TrEMBL, UniParc (The UniProt Archive), and GOA (Gene Ontology annotation of UniProt)
Data Sources
The individual data sources, together with some example queries are presented in the table below:
| DSN (Data Source Name) | Type | Description | Coordinate Systems | Example Queries | |
|---|---|---|---|---|---|
| Sequence Request | Features Request | ||||
| uniprot | Reference Server | UniProtKB | UniProtKB Accession numbers e.g. O35502 | sequence | features |
| Swiss-Prot ID e.g. A4_HUMAN | sequence | features | |||
| uniparc | Reference Server | UniProt Archive (UniParc) | UniParc ID e.g. UPI0000125656 | sequence | features |
| uniprot-tryptic | Annotation Server | Theoretical tryptic peptides based upon a complete and successful digest of the requested UniProtKB protein with trypsin. | UniProtKB Accession numbers e.g. O35502 | - | features |
| Swiss-Prot ID e.g. A4_HUMAN | - | features | |||
| uniprot-goa | Annotation Server | GO Annotation of UniProtKB | UniProtKB Accession numbers e.g. P99999 | - | features |
| Swiss-Prot ID e.g. A4_HUMAN | - | features | |||
Project Support
The 'UniProt DAS Service Project' is supported by UniProt team at EBI
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