- Course overview
- Search within this course
- What is UniProt?
- Where does the data come from?
- Why do we need UniProt?
- When to use UniProt
- Quiz: Check your learning I
- How to access and navigate UniProt
- How to search UniProt
- Annotation score
- Quiz: Check your learning II
- Exploring a UniProtKB entry
- How to use UniProt tools
- How to get data from UniProt
- How to submit data to UniProt
- When to use UniProt: guided examples
- Exercise: finding entries with 3D structures
- Exercise: mapping other database identifiers to UniProt
- Summary
- Get help and support on UniProt
- References
- Next steps
- Your feedback
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Why do we need UniProt?
Understanding protein function is critical to research in many areas of science such as biology, medicine and biotechnology. As the number of completely sequenced genomes continues to increase, huge efforts are being made in the research community to understand as much as possible about the proteins encoded by these genomes. This work is generating large amounts of data which are spread across multiple locations including scientific literature and many biological databases.
Keeping up with all of this information is a daunting task for most researchers. UniProt helps with this in the following ways:
- It provides an up-to-date, comprehensive body of protein information at a single site
- It aids scientific discovery by collecting, interpreting and organising this information so that it is easy to access and use
- It saves researchers countless hours of work in monitoring and collecting this information themselves
- It provides tools to help with protein sequence analysis
- It provides links to related information in more than 180 other biological databases to help you access additional information in more specialised collections
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