- Course overview
- Search within this course
- What is UniProt?
- Where does the data come from?
- Why do we need UniProt?
- When to use UniProt
- Quiz: Check your learning I
- How to access and navigate UniProt
- How to search UniProt
- Annotation score
- Quiz: Check your learning II
- Exploring a UniProtKB entry
- How to use UniProt tools
- How to get data from UniProt
- How to submit data to UniProt
- When to use UniProt: guided examples
- Exercise: finding entries with 3D structures
- Exercise: mapping other database identifiers to UniProt
- Summary
- Get help and support on UniProt
- References
- Next steps
- Your feedback
All materials are free cultural works licensed under a Creative Commons Attribution 4.0 International (CC BY 4.0) license, except where further licensing details are provided.
References
UniProt overview
These papers give an overview of the UniProt project:
- The UniProt Consortium. (2021) UniProt: the universal protein knowledgebase in 2021. Nucleic Acids Res. 49:D480-D489
- Wang Y, Wang Q, Huang H, Huang W. Chen Y, McGarvey PB, Wu CH, Arighi CN, UniProt Consortium (2021) A crowdsourcing open platform for literature curation in UniProt. Plos Biology. 19(12):e3001464. DOI: 10.1371/journal.pbio.3001464
- MacDougall A, Volynkin V, Saidi R, Poggioli D, Zellner H, Hatton-Ellis E, Joshi V, O’Donovan C, Orchard S, Auchincloss AH, Baratin D, Bolleman J, Coudert E, de Castro E, Hulo C, Masson P, Pedruzzi I, Rivoire C, Arighi C, Wang Q, Chen C, Huang H, Garavelli J, Vinayaka CR, Yeh LS, Natale DA, Laiho K, Martin MJ, Renaux A, Pichler K, UniProt Consortium. (2020) UniRule: a unified rule resource for automatic annotation in the UniProt Knowledgebase. Bioinformatics. 36(17) 4643-4648. doi:10.1093/bioinformatics/btaa485.
- Garcia L, Bolleman J, Gehant S, Redaschi N, Martin M, UniProt Consortium. (2019) FAIR adoption, assessment and challenges at UniProt. Sci Data. 2019 Sep;6(1) 175. doi:10.1038/s41597-019-0180-9.
- Pichler K, Warner K, Magrane M, UniProt Consortium. SPIN: Submitting Sequences Determined at Protein Level to UniProt. Curr Protoc Bioinformatics. 2018 Jun;62(1) e52. doi:10.1002/cpbi.52.
- Suzek B.E., Huang H., McGarvey P., Mazumder R., Wu C.H. (2007) UniRef: comprehensive and non-redundant UniProt reference clusters. Bioinformatics 23:1282-1288
- Leinonen R., Diez F.G., Binns D., Fleischmann W., Lopez R., Apweiler R. (2004) UniProt Archive. Bioinformatics 20:3236-3237
Read more
You can find additional papers about the project on the UniProt website.