Annotation score

What is the annotation score?

The annotation score provides a measure of the annotation content of a UniProtKB entry or proteome. It is a 5-point heuristic scoring system where a score of 5 is associated with the best-annotated entries, and a score of 1 with entries with basic annotation.

Where can I find the annotation score?

The annotation score of an entry can be found in the summary section at the top of each entry (Figure 21).

Adding annotation scores to search results

You can add annotation scores to your search results table through the ‘Columns’ button (Figure 22). When this is checked, a ‘Customize columns’ box will open and you can select additional fields to display on the Table view.

How are annotation scores used?

There are several contexts in which annotation scores can be used:

• UniProtKB – the annotation scores can help you to get a quick idea of the relative level of annotation of the entries in your search results
• UniRef – UniProt uses annotation scores to select the representative member of a UniRef cluster
• Reference proteomes – UniProt uses annotation scores to assist with the selection of reference proteomes

How are annotation scores calculated?

• Different UniProtKB annotation types are scored either by presence or by number of occurrences. Annotations with experimental evidence score more highly than equivalent predicted annotations, thereby favouring expert literature-based curation over automatic annotation.
• The score of an individual entry is the sum of the scores of its annotations.