- Course overview
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- InterPro and protein signatures
- Case study 1: SFLD
- Case study 2: TIGRFAMs
- Case study 3: PANTHER
- Comparison of protein signatures
- Predicting protein signature relationships
- Summary
- Your feedback
- Get help and support on InterPro
- References
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Summary
- InterPro integrates protein signatures from multiple member databases into a single searchable resource
- The member databases employ various methods of producing signatures, and cover a range of biological focuses
- Even similar resources (such as the 3 case studies) employ subtly different methods of generating signatures
- It is possible to automatically compare these signatures to generate predicted hierarchies of protein signature models
- These predictions can greatly assist in the manual process of integrating signatures into InterPro entries