Reactome: Tools for analysis of biological pathways

Overview with overrepresentation analysis results

This course introduces the tools available via the Reactome pathway database web interface. For a short introduction to Reactome, please visit the Reactome quick tour.  For an intruduction to the Reactome web interface including the Pathway Browser, please visit the Introduction to Reactome.

An undergraduate degree in a life science subject or background knowledge in molecular biology will be an advantage. You may want to look at the conceptual introducion 'Protein interactions and their importance' and Reactome: Exploring biological pathways, before taking this course.

Last updated May 2017.

About this course

Steve Jupe
Learning objectives: 
  • Be able to map your own list of gene, protein, or compound identifiers to Reactome pathways and identifying the pathways that are over-represented
  • Visualise pathway expression levels using your own microarray or protein expression dataset
  • Extend Reactome pathways with protein-protein or protein-compound interactions from relevant databases or your own interactions data
  • Compare curated human pathways with computationally predicted pathways in other species