Course content

To see details about the live Cancer genomics and transcriptomics course and the original programme, you can refer to the course page and programme.

The contents table below outlines the different sessions that were included in the course, as well as the format of the materials (slides/videos/practicals) and each session’s trainer. Either proceed through the materials using the arrows at the end of each page or pick your topic of interest from the table below to skip straight to it.

 Presentation slides –  View or download the slides

 Recorded lectures – Watch the lecture videos 

Practicals – View or download the slides, exercises, datasets, analysis scripts and results

FormatSubjectTrainer
Introduction to cancer genomics and transcriptomics
Introduction to cancer genomics and its caveats Tobias Rausch 
High-throughput sequencing and single-nucleotide variant analysis in cancerDaniela Robles-Espinoza
Practical: Alignment and SNV analysisDaniela Robles-Espinoza, Patricia Basurto and Kenya Lizbeth Contreras-Ramírez
Structural and copy number variation, and mutational signatures
Structural and copy-number variation analysisTobias Rausch 
Practicals: SV/CNV analysis using short-readsTobias Rausch 
Interrogating cancer genomes using long readsTobias Rausch 
Mutational processes and clonal population structure in cancer genomesTobias Rausch
Single-cell sequencing in cancer
Introduction to single-cell technologies in cancer genomicsDeniz Demircioglu
Introduction to single-cell technologies in cancer genomics: practicals and troubleshootingDeniz Demircioglu
Practical: Deconvolution of the clonality of a tumor using single-cell transcriptomic dataEstefania Vázquez and Gabriel Pereira
RNA-Seq analysis in cancer research
Short-read RNA-seq analysisAlexey Larionov
Long-read RNA-seq analysisAlexey Larionov
CRISPR-Cas9
CRISPR-Cas9 genome editing for identifying cancer dependencies and new therapeutic targetsFrancesco Iorio
Pre-processing, QC assessment, and visualisation of gene essentiality profiles from CRISPR-Cas9 screens (practicals and troubleshooting)Francesco Iorio
Epigenetics
Epigenetics lectureSaul Carcamo
Epigenetics practicalSaul Carcamo
Further learning