The Cancer genomics and transcriptomics course, which  focused on the analysis of data from genomic studies of cancer, ran virtually in May 2025. Here, we have made the course materials available for you to access any time.

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Using these materials

These course materials provide a mixture of pre-recorded lectures, presentations and practicals to help advance your skills in the analysis of cancer genomics data. You may select your topic of interest from the Course content page to view the relevant materials or work your way through all the course materials. 

To find out more about the trainers who created these materials, follow the links from the Course content page or go directly to the Trainer biographies page. You can also find the software requirements for the practicals in the Technical help sheet.

In the Further learning section you may explore the details about the EMBL-EBI’s free access online tutorials and webinars on a variety of life sciences topics.

If you would like to provide feedback on this set of course materials, please use the form on the Your feedback page.

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Learning outcomes

After the course you should be able to:

• Evaluate the applications and challenges of HTS in the study of cancer genomics
• Detect, visualise, and annotate copy number variation
• Interpret complex genomic rearrangements such as structural variants
• Explain the principles of tumour purity, heterogeneity, and evolution and how we detect or quantify them using bioinformatic approaches
• Explore the application of CRISPR-Cas9 genome editing in cancer studies
• Perform alignment and quantification of expression of RNA-seq datasets
• Explore the application of single-cell sequencing in cancer studies

Material collection editors

• Patricia Carvajal Lopez, EMBL-EBI
• Isidro Cortes Ciriano, EMBL-EBI
• Ajay Mishra, EMBL-EBI
• Tobias Rausch, EMBL

DOI: 10.6019/TOL.CancerGenomics-t.2021.00001.1