Shared Data, Shared Costs

Date:

  Wednesday 18 June 2014

Application deadline: 

Wednesday 04 June 2014

Contact: 

Holly Foster

Registration closed

Overview

Background and motivation
This workshop has been scheduled to follow the publication of a Nature Reviews Drug Discovery editorial on pre-competitive opportunities to generate reference biological datasets (NRDD, 13(2) 83-84) "Precompetitive activity to address the biological data needs of drug discovery". The purpose of the workshop is to link those with shared interests, to identify areas of need as well as to maximise the impact and sustainability of these resources. The workshop will also discuss funding models and relationships with funding agencies/academic partners.

Biologists engaged in drug target discovery, validation and safety evaluation routinely require reference biological data to answer apparently simple questions, such as: "In which tissues is my target gene expressed?" However, as the complexity of biological knowledge increases, so do their expectations. For example, the question becomes: "What splice variants exist for my target gene, and in which tissues are they expressed?"

The focus of the workshop will be on: small pre-competitive projects to generate reference biological data sets' such as the Cell Line Repository, Causal Interactions database and Splice variant expression atlas.'

The aims of the workshop are to:

  • Present some examples of pre-competitive project discussions that have been generated through the EMBL-EBI Industry Programme.
  • Identify additional areas of interest that could the basis for future pre-competitive projects
  • Connect and encourage discussion between Pharma, SMEs and other potential funders/stakeholders.
  • Discuss mechanisms for kick-starting future pre-competitive projects.
  • Understand different types of open innovation.
  • Exploring funding models.

Participation
Participation is open to members of the EMBL-EBI Industry programme AND any other interested parties (small registration charge of £60 as a contribution to cost of catering).
As part of the registration process individuals who wish to present on the afternoon of June 18 are invited to submit an abstract to propose a presentation (closing date May 29th 2014). The organising
committee will then decide which proposals most closely match the theme of the workshop and individuals submitting proposals will be contacted by the organisers. The proposals most closely related to the theme of the workshop will be added to the agenda on the afternoon of 18 June with additional discussion on 19 June. Details of how to submit your abstract will be given in your registration confirmation email.

Additional information

If you require accommodation, please ensure you arrange this well in advance. Accommodation is not included in this course.

We would recommend you book accommodation with the Wellcome Trust Conference Centre You will need to book this as soon as possible as availability is often limited. Please contact their reception, Tel: +44 (0) 1223 495000 or email: reception@wtconference.org.uk

or you can book with The Red Lion, Hinxton, Cambridgeshire CB10 1QY, (Tel: +44(0) 1799 530601) which has 8 rooms available.  

Alternatively you can contact the Holiday Inn Express Duxford 42 Station Road, East Whittlesford Bridge, Cambridge CB22 4NL (located next to Whittlesford Train Station)  (Tel: +44(0) 1223 497070) which has 75 rooms available.

Details regarding travel to the EBI South Building Kendrew Lecture Theatre can be found here //www.ebi.ac.uk/about/travel

This workshop is coordinated through the EMBL-EBI industry programme. Please send any questions regarding the strategic intent and workshop agenda to Dominic Clark (clark@ebi.ac.uk), Industry Programme Manager, EMBL-EBI.
Please send any questions regarding logistics and registration to Holly Foster (holly@ebi.ac.uk).

Industry Programme workshop topics are selected by our members in order to promote precompetitive knowledge exchange.

Programme

Time Topic Speaker
Day 1 - Wednesday 18 June 2014
10:00 Registration and Coffee  
10:30 Welcome: background to the EMBL European Bioinformatics Institute and workshop overview Dominic Clark, Industry Programme manager  (EMBL-EBI)
11:00 Overview of the Pistoia Alliance  Simon Thornber (GSK)
11:30 Precompetitive activity to address the biological data needs of drug discovery  Ben Sidders (Pfizer Neusentis)
11:50 Discussion   
12:00 The integrated Cell Line Repository project  Bertram Weiss (Bayer Pharma)
12:30 Lunch and Networking   

13:45

Causal Interactions and the IntAct Molecular interaction database  Sandra Orchard (EMBL-EBI)
14:05 Discussion   
14:15 Building Research Datamarts: In Praise of Disposable Infrastructure and Enduring Data Michael R. Barnes (Director of Bioinformatics, William Harvey Research Institute, Queen Mary University of London)
14:45 Early Stage Strategy for Antibiotic discovery from Marine Bacteria Lisa Crossman (Director, SequenceAnalysis.co.uk & Honorary Lecturer, School of Biological Sciences, University of East Anglia, UK)
15:15 Coffee break   
15:45 The Polarised Vision of Bioinformatics Jim Reynolds (Chairman at General Bioinformatics)
16:15 Modulation of Alternative Splicing by Therapeutic Intervention Sushma Nagaraja Grellscheid (Lecturer in Genomics, Durham University, UK)
16:45 Break out discussions in Foyer area   
17:45 Closing comments for day 1  Dominic Clark (EMBL-EBI) & Ben Sidders (Pfizer Neusentis)
18:30 Pre-dinner drinks   
19:15 Dinner at Hinxton Hall, Wellcome Trust Genome Campus  
21:30 Departures  
Day 2 - Thursday 19 June 2014
09:00 Coffee   
09:30 Open Phacts: Lessons in pre-competitive collaboration  Lee Harland (Connected Discovery)
10:00 Plenary discussion based on break out groups
11:00 Closing panel discussion and next steps  moderator: Dominic Clark (EMBL-EBI), panellists: industry co-organisers
11:30 End of workshop (delegates are welcome to have lunch in Murrays canteen on campus