PDBsum entry 9ima

Membrane protein/immune system

PDB id: 9ima

Contents

Protein chains

221 a.a.

214 a.a.

249 a.a.

Ligands

CLR ×6

PDB id:

9ima

Name:

Membrane protein/immune system

Title:

Cryo-em structure for the gprc5d complexed with talquetamab fab

Structure:

Talquetamab fab (anti-gprc5d) heavy chain. Chain: c. Engineered: yes. Talquetamab fab (anti-gprc5d) light chain. Chain: d. Engineered: yes. G-protein coupled receptor family c group 5 member d. Chain: b, a. Engineered: yes

Source:

Mus musculus. Organism_taxid: 10090. Expressed in: trichoplusia ni. Expression_system_taxid: 7111. Homo sapiens. Human. Organism_taxid: 9606. Gene: gprc5d. Expressed in: homo sapiens.

Authors:

J.Jeong,J.Shin,J.Park,Y.Cho

Key ref:

J.Jeong et al. (2024). Structural basis for the recognition of gprc5d by talquetamab, A bispecific antibody for multiple myelo. J mol biol, 436, 68748. PubMed id: 39181182

Date:

02-Jul-24 Release date: 11-Sep-24

Protein chain

No UniProt id for this chain

Struc: 221 a.a.

Protein chain

No UniProt id for this chain

Struc: 214 a.a.

Protein chains

Q9NZD1  (GPC5D_HUMAN) -  G-protein coupled receptor family C group 5 member D from Homo sapiens

Seq: 345 a.a.

Struc: 249 a.a.