PDBsum entry 9jhj

Membrane protein

PDB id: 9jhj

Contents

Protein chains

293 a.a.

215 a.a.

336 a.a.

50 a.a.

211 a.a.

Ligands

18C

PDB id:

9jhj

Name:

Membrane protein

Title:

Cryo-em structure of the c18:0 ceramide-bound fpr2-gi complex

Structure:

N-formyl peptide receptor 2. Chain: r. Synonym: fmlp-related receptor i,fmlp-r-i,formyl peptide receptor- like 1,hm63,lipoxin a4 receptor,lxa4 receptor,rfp. Engineered: yes. Guanine nucleotide-binding protein g(i) subunit alpha-1. Chain: a. Synonym: adenylate cyclase-inhibiting g alpha protein. Engineered: yes.

Source:

Homo sapiens. Human. Organism_taxid: 9606. Gene: fpr2. Expressed in: spodoptera frugiperda. Expression_system_taxid: 7108. Gene: gnai1. Gene: gnb1. Gene: gng2.

Authors:

J.P.Sun,C.T.Jiang,W.Kong,X.Yu,K.Cai,L.L.Guo

Key ref:

J.P.Sun et al. Metabolic signaling of ceramides through the fpr2 rec inhibits adipocyte thermogenesis. Science, . PubMed id: 40080544

Date:

09-Sep-24 Release date: 19-Mar-25

Protein chain

P25090  (FPR2_HUMAN) -  N-formyl peptide receptor 2 from Homo sapiens

Seq: 351 a.a.

Struc: 293 a.a.

Protein chain

P63096  (GNAI1_HUMAN) -  Guanine nucleotide-binding protein G(i) subunit alpha-1 from Homo sapiens

Seq: 354 a.a.

Struc: 215 a.a.

Protein chain

P62873  (GBB1_HUMAN) -  Guanine nucleotide-binding protein G(I)/G(S)/G(T) subunit beta-1 from Homo sapiens

Seq: 340 a.a.

Struc: 336 a.a.

Protein chain

P59768  (GBG2_HUMAN) -  Guanine nucleotide-binding protein G(I)/G(S)/G(O) subunit gamma-2 from Homo sapiens

Seq: 71 a.a.

Struc: 50 a.a.

Protein chain

No UniProt id for this chain

Struc: 211 a.a.

Enzyme reactions

• Enzyme class: Chain A: E.C.3.6.5.- - ?????