PDBsum entry 8zbj

Membrane protein

PDB id: 8zbj

Contents

Protein chains

336 a.a.

54 a.a.

218 a.a.

264 a.a.

167 a.a.

Ligands

ASN-PHE-PHE-TRP-LYS-THR-PHE-THR

PDB id:

8zbj

Name:

Membrane protein

Title:

Cryo-em structure of somatostatin receptor 5 (sstr5) with gi1 complex

Structure:

Somatostatin-14. Chain: s. Synonym: sst14. Engineered: yes. Guanine nucleotide-binding protein g(i)/g(s)/g(t) subunit beta-1. Chain: c. Synonym: transducin beta chain 1. Engineered: yes.

Source:

Homo sapiens. Human. Organism_taxid: 9606. Gene: sst. Expressed in: synthetic construct. Expression_system_taxid: 32630. Gene: gnb1. Expressed in: spodoptera frugiperda. Expression_system_taxid: 7108.

Authors:

Y.Kim,J.H.Yun

Key ref:

Y.Heo et al. The structure of sstr3 and sstr5 provide insights int specificity among somatostatin receptos.. To be published, .

Date:

26-Apr-24 Release date: 30-Apr-25

Protein chain

P62873  (GBB1_HUMAN) -  Guanine nucleotide-binding protein G(I)/G(S)/G(T) subunit beta-1 from Homo sapiens

Seq: 340 a.a.

Struc: 336 a.a.

Protein chain

P59768  (GBG2_HUMAN) -  Guanine nucleotide-binding protein G(I)/G(S)/G(O) subunit gamma-2 from Homo sapiens

Seq: 71 a.a.

Struc: 54 a.a.

Protein chain

No UniProt id for this chain

Struc: 218 a.a.

Protein chain

P0ABE7  (C562_ECOLX) -  Soluble cytochrome b562 from Escherichia coli

Seq: 128 a.a.

Struc: 264 a.a.*

Protein chain

P35346  (SSR5_HUMAN) -  Somatostatin receptor type 5 from Homo sapiens

Seq: 364 a.a.

Struc: 264 a.a.

Protein chain

P63096  (GNAI1_HUMAN) -  Guanine nucleotide-binding protein G(i) subunit alpha-1 from Homo sapiens

Seq: 354 a.a.

Struc: 167 a.a.*

* PDB and UniProt seqs differ at 155 residue positions (black crosses)